摘要
目的:建立治冻灵中樟脑含量的气相色谱测定法。方法:色谱柱:聚乙二醇20M弹性石英毛细管柱(CPWAX52CB,30m×0.25mm,DF=0.25μm);FID检测器;水杨酸甲酯为内标。结果:樟脑的线性范围0.9755-4.8776mg·mL^-1,r=0.9999,平均加样回收率98.48%(RSD=1.29%,n=6)。结论:该方法准确,简便,可有效控制制剂的质量。
Objective: To develop a GC method for the determination of camphor in Zhidongling ointment. Method: Gas chromatographic column: PEG-20M capillary columns (CP WAX 52 CB, 30 m× 0. 25 mm, DF = 0. 25 μm) , FID. Methyl salicylate was used as internal standard. Result: The linear range of camphor was 0. 975 5 - 4. 877 6 mg· mL^-1, the average recovery was 98.48 %, RSD 1.29%. Conclusion: The method is simple and sensitive. It could be used for the quality control of Zhidongling ointment.
出处
《药学与临床研究》
2007年第6期509-510,共2页
Pharmaceutical and Clinical Research
关键词
樟脑
治冻灵软膏
气相色谱
含量测定
Camohor GC Zhidongling ointment Content determination