期刊文献+

巨噬细胞移动抑制因子及其与危重症相关性的研究进展

下载PDF
导出
摘要 巨噬细胞移动抑制网子(Macrophage migration inhibitory factor,MIF)系由T细胞产生的在体外能抑制巨噬细胞移动,并能在迟发型变态反应中促进巨噬细胞聚集的一种多功能细胞因子。近年来,在免疫和炎症反应过程中发现MIF作为一种关键性介质,作用广泛,特别是在全身性炎症反应综合征(Systemic inflammatory response syndrome,SIRS)中起到某种关键作用.MIF并在多种危重病中表达明湿升高,可促进多种危重疚病的发生、发展。现将MIF与部分危重病的相关性研究综述如下。
出处 《实用医药杂志》 2007年第12期1504-1506,共3页 Practical Journal of Medicine & Pharmacy
  • 相关文献

参考文献17

  • 1Calandra T, Roger T. Maerophage migration inhibitory factor:, a regulator of innate immunity. Nat Rev Immunol, 2003,3(10):791.
  • 2Bernhagen J, Calandra T, Bucala R, et al. Regulation of the Immune response by macrophage migration inhibitory factor:biological and structure features. J Mol Med, 1998,76:151.
  • 3Apte RS, Mayhew SE, Wistow G J, etal. Role of macrophage inhibitory factor in inhibiting NK cell activity and preserving immune privilege. J Immunol, 1998,160:5693.
  • 4Lehmann LE, Novender U, Schroeder S, et al. Plasma levels of macrophage migration inhibitory factor are elevated in patients with severe sepsis. Intensive Care Med, 2001,27:1412.
  • 5Beishuizen A, Thijs LG, Haanen C, et al. Macrophage migration inhibitory factor and hypothalamo-pituitary-adrenal function during critical illness. J Clin Endorcrinol Metab, 2001,86:2811.
  • 6Joshi PC,Poole GV,Sachdev V,et al.Trauma patients with positive cultures have higher levels of circulating macrophage migration inhibitory factor (MIF).Res Commun Mol Pathol Pharmacol, 2000, 107(1):13.
  • 7Bather M,Meinhardt A,Lan HY,et al. Migration inhibitory factor expression in experimentally induced endotoxemia. Am J Pathol, 1997,150:235.
  • 8Bernhagen J,Calandra T,Mitchell RA, et al. MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia.Nature, 1993, 365:756.
  • 9Calandra T, Echtenacher B,Roy DL.et al. Protection from septic shock bY neutralization of macrophage migration inhibitory factor Nat Med, 2000, 6: 164.
  • 10Hochrein J, Bashore TM, O'Laughlin MP,et al.percutaneous stentiug of superior vena cava syndrome: a case report and review of the literature.Am J Med, 1998,104:78.

二级参考文献8

  • 1Bloom BR,Bennett B.Mechanism of a reaction in vitro associated with delayed-type hypersensitivity[J].Science,1966,153:80-82.
  • 2Bernhagen J,Calandra T,Mitchell RA,et al.MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia[J].Nature,1993,365:756-759.
  • 3Bacher M,Meinhardt A,Lan HY,et al.MIF expression in experimentally-induced endotoxemia[J].Am J Pathol,1997,150:235-246.
  • 4Calandra T,Echtenacher B,Roy DL,et al.Protection from septic shock by neutralization of macrophage migration inhibitory factor[J].Nat Med,2000,6:164-170.
  • 5Bozza M,Satoskar AR,Lin G,et al.Targeted disruption of migration inhibitory factor gene reveals its criticalrole in sepsis[J].J Exp Med,1999,189:341-346.
  • 6Calandra T,Berhhagen J,Mitchell RA,et al.The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor(MIF)[J].J Exp Med ,1994,179:1895-1902.
  • 7Bacher M,Metz CN,Calandra T,et al.An essential regulatory role for macrophage migration inhibitory factor in T-cell activation[J].Proc Natl Acad Sci U S A,1996,93:7849-7854.
  • 8Calandra T,Bernhagen J,Metz CN,et al.MIF as a glucocorticoid-induced modulator of cytokine production[J].Nature, 1995,377:68-71.

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部