动态血压与偶测血压应用指导高血压治疗比较

Comparison between ambulatory blood pressure and chance blood pressure guiding treatment of hypertension

双盲法观察连续６个月用动态血压（ｐＡＢ）和偶测血压（ｐＣＢ）指导治疗高血压各１０例的联合用药阶梯差异和异常心电图、副作用发生例数及左心室质量指数（ＬＶＭＩ）的变化。结果将血压降至预定水平ｐＣＢ组采用第Ⅱ阶梯治疗以上方案共７例，ｐＡＢ组共２例（Ｐ＜０．０５）。发生不良反应ｐＣＢ组３７２例次，ｐＡＢ组１０８例次（Ｐ＜０．０５）。心电图异常及ＬＶＭＩ变化两组间无差异（Ｐ均＞０．０５）。提示ｐＣＢ组可能受到“白大衣高血压”现象的影响低估了降压幅度，致用药过量或过度降压。ｐＡＢ组克服了这一影响，用于指导治疗高血压时，ｐＡＢ优于ｐＣＢ。

This double blind study assessed the difference of drug does and the grade of combined drugs,num ber of abnormal electrocardiogram (ECG),left ventricular mass index (LVMI) and the number of side effect between the two groups of hypertensio