钙化性胃癌的CT表现及其病理基础的研究

Study of CT feature and pathologic characteristics of calcified gastric carcinoma

目的:探讨钙化性胃癌的CT表现及其病理基础。方法:对19例钙化性胃癌术前行CT扫描,分析其CT表现的特点,并与手术病理结果进行对照、分析。结果:19例钙化性胃癌Borrmann分型均为弥漫型,病理类型为黏液腺癌、印戒细胞癌及富含黏液的低分化腺癌。CT表现为病灶胃壁弥漫性增厚,增厚的胃壁内见带状低密度灶或全层呈带状低密度,低密度灶内可见弥漫性分布、大小不一的钙化颗粒。低密度带的CT值为(22.34±3.24)HU,CT值经t检验,具有统计学意义(P值均<0.05)。病理表现为肿瘤组织及间质内含有丰富的黏液,其内可见多发钙化灶弥漫分布。结论:钙化性胃癌具有特征性的影像表现及病理基础,其恶性程度高,预后较差,这对于临床治疗方案的制定具有指导意义。

Objective： To study CT features and pathologic characteristics of calcified gastric carcinoma. Method： The CT features of calcified gastric carcinoma in 19 patients were analyzed before operation, also were correlated with pathologic characteristics after operation. Results： The Borrmann＇s classification of lesions in the 19 patiens were all Borrmann IV. The pathological types of the lesions in the 19-patiens were gastric mucoid adenocarcinoma, signet ring carcinoma, poorly differentiation adenocarcinoma abundant with mucous. In CT image, diffuse thickening of gastric wall with the belt of lower density in lesion or lower density in all the lesion was observed, while calcified granules were diffusely distributed in the lesion. The CT value was （22.34±3.24）HU, which was statistically singnificant （P〈0.05） by t test. The pathological features were that tumour tissue and mesenchyme were abundant with mucous and calcified area scattered within the lesion, the tumor cells infiltrated along the stomach wall. Conclusion： Calcified gastric carcinoma has special CT image and special pathology features. Calcified gastric carcinoma was poorly differentiated, and high malignancy and with poorest prognosis. It was of great significance in diagnosis and treatment of calcified gastric carcinoma.