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siRNA分子选择性的导入靶组织细胞的方法 被引量:2

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摘要 1998年,Fire等对秀丽新小线虫做了各种类型RNA(针对靶基因的单链反义RNA)深入研究,双链RNA能够产生比单链RNA更有效、更强的阻抑效应。以后,RNAi技术逐步用于各研究领域。发展到现在,siRNA给药途径及如何选择性地把siRNA导人需要进行基因沉默的靶组织和靶细胞是RNAi目前临床应用的困扰。
作者 倪春 张才全
出处 《重庆医学》 CAS CSCD 2007年第24期2572-2574,共3页 Chongqing medicine
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