床边快检肌钙蛋白Ⅰ和肌红蛋白在急性心肌梗塞早期诊断中的应用

Clinical application of cTnI and Mb quickly testing in bedside for early diagnosing acute myocardial infarction

目的:探讨床边快检心肌肌钙蛋白I(cTnI)、肌红蛋白(Mb)在急性心肌梗塞(AMI)早期诊断中的应用以及二项之间的相互关系。方法:选择96例疑似ACS患者的血液标本,在不同时段,同时进行cTnI和Mb的测定。结果:在确诊的87例AMI早期诊断中,cTnI阳性出现滞后,3h内测定的阳性率为16.1%,显著低于Mb的阳性率(72.4%),P<0.01;24h内测定cTnI的阳性率为100%。结论:在急诊科床边快检cTnI与Mb对AMI的早期诊断非常必要,可起到优势互补的作用。

Objective： To evaluate the clinical application of cardiac troponin Ⅰ（cTnⅠ） and myohemoglobin （Mb） quickly testing in bedside for early diagnosing acute myocardial infarction （AMI） and correlation between cTnⅠ and Mb. Methods： The plasma cTnⅠ and Mb in 96 AMI patients were measured at the same time at different time stage. Results. In 87AMI patients early diagnosed, the positive rate of cTnⅠ within 3h was 16.1%, it was less than that of Mb （72.4%）, P〈0. 01; within 24h it was 100%, therefore have definite significance. Conclusion： The cTnⅠ and Mb quickly testing in bedside for early diagnosing AMI are extremely essential, and they have superiority complementary effect.