摘要
为研究牛蒡低聚果糖(BFOS)对小鼠的抗疲劳作用,将牛蒡低聚果糖用三个不同剂量组100、200、400mg.kg-1.d-1给小鼠灌胃,对照组为生理盐水,连续灌胃42 d,末次饲喂30 min后进行游泳实验,耐缺氧实验,测定运动耐力、血乳酸(LAC)、血尿素氮(BUN)等指标。测试结果表明三个剂量的牛蒡低聚果糖均能显著提高运动耐力和耐缺氧时间;降低运动后LAC和BUN的含量;提高肌、肝糖元含量。说明牛蒡低聚果糖具有良好的抗疲劳作用,200 mg.kg-1.d-1为最佳用量,高剂量无明显优势。
In order to study the antifatigue effect of burdock fructooligsaccharide （ BFOS）, mice were divided into four groups,supplemented with BFOS at the doses of 100,200,400 mg·kg^-1·d^-1 and 0.9 sodium chloride solution respectively. After 42 d,swimming time and survival time under hypoxia were measured. BUN and blood LAC after swimming were measured also. The results showed three dose of BFOS increased swimming time and survival time under hypoxia, and decrease of serum BUN and LAC in swimming mice. From these observations it is concluded that BFOS has antifatigue effect and its optimum dose is 200 mg·kg^-1·d^-1.
出处
《天然产物研究与开发》
CAS
CSCD
2007年第4期642-644,共3页
Natural Product Research and Development
基金
皖南医学院引进人才启动基金(k80169)
