摘要
左旋咪唑(levamisoIe,LMS)是一种经典的广谱驱虫药及免疫调节剂,随着在临床上广泛的应用和各种检查技术的提高,其ADR也逐渐被人们所认识,其中以急性播散性脑脊髓炎(ADEM)最为严重,临床表现复杂,容易被忽视,后果较为严重。早期诊断和及时的肾上腺糖皮质激素的治疗对本病的预后有重要意义。
Levamisole is a classic broad-spectrum anthelminthin agent and immunomodulator. The adverse reactions are being gradually realized as levamisole generally was under wide administration in clinical practice and various kinds of laboratory examination were improved. Acute disseminated encephalomyelitis caused by levamisole therapy is one of the most serious adverse effects. The disease has a complicated clinical manifestation and is usually ignored, so that it may lead to serious consequence. Prompt diagnosis and concomitant admini-stration of glucocorticoids may result in more rapid clinical and radiographic resolution.
出处
《抗感染药学》
2007年第4期181-183,共3页
Anti-infection Pharmacy
