摘要
细胞S期激酶相关蛋白是泛素-蛋白酶体通路中E3连接酶-SCF复合物的底物识别序列,是一种癌蛋白,与细胞周期调控因子、癌基因、抑癌基因关系密切,对细胞周期G1/S期关卡起调控作用,在许多恶性肿瘤中表达增高,与肿瘤的发生、发展、浸润及转移关系密切,可以作为判断肿瘤预后的一个有价值的预后指标,并可以作为抗癌药物和基因治疗的新靶点。
出处
《国外医学（妇产科学分册）》
2007年第6期409-412,共4页
Foreign Medical Sciences(Obstet Gynecol Fascicle)
参考文献20
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