柴胡红景天化学成分的研究

Chemical Constituents in Root of Rhodiola bupleuroides

采用正相与反相硅胶柱色谱和薄层色谱分离纯化的方法,从景天科红景天属植物柴胡红景天(Rhodiola bupleuroides)根茎70%乙醇提取物的乙酸乙酯萃取部分中分离得到7个化合物,用光谱分析(UV,IR,MS,1H-NMR,13C-NMR)和化学反应鉴定化合物分别为:没食子酸(1)、山奈酚-7-O-α-L-吡喃鼠李糖苷(2)、草质素-7-O(3″-O-β-D-葡萄糖基)-α-L鼠李糖苷(3)、槲皮素(4)、丁香酸(5)、3,5-二甲氧基-4-羟基-苯甲酸-7-O-β-D-葡萄糖苷(6)、β-谷甾醇(7).以上化合物均为首次从该植物中分离得到,其中化合物5和6为首次从红景天属植物中发现.

Seven compounds were isolated from the extraction fraction of ethyl acetate which is extracted from the 70% ethanol extract of Rhodiola bupleuroides rhizome by silic gel column chromatography and preparative thin layer chromatography （Prep-TLC）,and structurally identified by spectral technology and chemical methodology. They are gallic acid （ 1 ）, kaempferol-7-O-α-L-rhamnopyranoside （ 2）, rhodiosin （3）, quercetin（4）, syringic acid （5）, 3,5-dimethoxy-4-hydroxy benzene carbonic-7-O-β-D-pyranglucose （ 6 ）, β-sitosterol（7）. All the compounds were isolated from this plant for the first time,and 5,6 were isolated from this genus for the first time.