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TGF-β、IL-17与骨性关节炎研究新进展 被引量：6

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摘要 骨性关节炎（osteoarthritis，OA），又称骨关节病、退行性关节病、增生性关节炎、肥大性关节炎、老年性关节炎，是最常见的一种慢性、进展性关节疾病。其病理特点为关节软骨变性、破坏、软骨下骨硬化、关节边缘和软骨下骨反应性增生、骨赘形成。该病病程长，病因不明确，致残率高，给患者本人及社会带来极大的损失。
作者 孙义忠 张志刚
机构地区 华北煤炭医学院 唐山市第二医院关节科
出处 《中国骨肿瘤骨病》 2007年第6期375-377,共3页 Chinse Journal Of Bone Tumor And Bone Disease
关键词 骨性关节炎 TGF-Β IL-17 退行性关节病 增生性关节炎 肥大性关节炎 关节软骨 反应性增生
分类号 R684.3 [医药卫生—骨科学]
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参考文献21

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  • 4[4]Tsukazaki T,Usa T,Matsumoto T,et al.Effect of transforming growth factor-beta on the insulin-like growth factor-I autocrine/paracrine axis in cultured rat articular chondrocytes.Exp Cell Res,1994,215:9-16.
  • 5尚显文,宁旭,尹培荣,吴承龙.TGF-β_1对体外培养兔软骨细胞增殖的研究[J].贵州医药,2004,28(6):487-489. 被引量：4
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二级参考文献7

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  • 7Tsukazaki T, Usa T, Matsumoto T,et al. Effect of transforming growth factor-β on the insulin-like growth factorⅠautocrine/paracrine axis in culture rat articular chondrocytes. Exp cell Res, 1994,215:9-15.

共引文献3

同被引文献83

引证文献6

二级引证文献107

中国骨肿瘤骨病
2007年 第6期

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