新诊断的2型糖尿病患者的动态血糖监测分析

Analysis of continuous glucose monitoring in newly diagnosed patients with type 2 diabetes mellitus

目的:探讨新诊断的2型糖尿病(T2DM)患者的动态血糖变化特点。方法:以动态血糖监测系统(CGMS)监测新诊断的T2DM患者72h血糖变化。结果:血糖的峰值以早餐后血糖较高,且达峰值的时间较快,中、晚餐后次之;CGMS检测值与指端血糖检测值(BGMS)及静脉血糖值呈正相关(r=0.891,P<0.01;r=0.834,P<0.01);FBG、PBG皆与HbA1c呈正相关(r=0.775,P<0.01;r=0.487,P<0.05);低血糖多发生在0:00～4:00,黎明现象多发生在5:00～7:00。结论:CGMS可全面地反映动态血糖水平,为T2DM患者的诊疗提供客观依据。

Objective：To detect changes of blood sugar in the patients with newly diagnosed type 2 diabetes mellitus （T2DM）. Methods：To monitor changes of blood sugar in the patients with newly diagnosed T2DM by continous glucose monitoring system （CGMS）. Results：Peak value of PBG was higher after breakfast than noon or supper, time of reaching peak value after breakfast was also faster than that of noon or supper. CGMS glucose values was that of positively correlated with BGMS glucose values or vein glucose values. FBG or PBG value was positively correlated with HbAlc value. Hypoglycemia often occurred at 0：00-4：00,and dawn phenomenon at 5：00-7：00 .Condusion：CGMS can entirely reflect the levels of continous blood sugar, and it can objectively offer basis of diagnosis and treatment to the patients with T2DM.