摘要
以3,4-二氯硝基苯为原料,经过高压水解和还原反应,合成了2-氯-4-氨基苯酚,再与全氟甲基乙烯基醚加成,得3-氯-4-[1,1,2-三氟-2-(三氟甲氧基)乙氧基]苯胺,总收率为72.0%,产物结构经元素分析、IR和1H NMR表征。该工艺具有原料易得、收率高、质量好、对环境污染小等特点。
2-Chloro-4-aminophenol was synthesized from 3,4-dichloronitrobenzene by high pressure hydrolysis and reduction reaction, afterwards the addition reaction with pedluoro-vinyl-pedluoro-methyl ether was conducted to synthesize 3-chloro-4- [ 1,1,2-trifluoro-2- (trifluoromethoxy) -ethoxy ] aniline. The overall yield was 72. 0%, the product structure was characterized by elemental analyses, IR spectra and 1H NMR,it has characteristics of ready availability of reactant, high yield, good quality, little pollution to environment.
出处
《应用化工》
CAS
CSCD
2007年第12期1249-1251,共3页
Applied Chemical Industry