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复方利多卡因喷雾剂的稳定性研究 被引量:1

Stability of compound Lidocaine hydrochloride spray
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摘要 目的:考察复方利多卡因喷雾剂的稳定性。方法:通过加速试验、长期试验,以高效液相色谱法(HPLC)测定复方利多卡因喷雾剂中盐酸利多卡因、硝酸甘油、氯霉素的含量,以及观测溶液的外观性状、pH值,考察本制剂的稳定性。结果:复方利多卡因喷雾剂在加速试验、长期试验中含量变化范围小,均在限度范围内,外观性状及pH值无明显变化。结论:复方利多卡因喷雾剂在室温贮藏条件下稳定性好。 Objective:To study the stability of the compound Lidocaine hydrochloride spray. Methods: We used high performance liquid chromatography to detect the content of Lidocaine hydrochloride, nitrolar and chlormycetin in compound Lidocaine hydrochloride spray and observed its appearance and characteristics,pH value and stability through accelerated test and long test run. Results:The content of Lidocaine hydrochloride,nitrolar and chlormycetin in compound Lidocaine hydrochloride spray showed a small change range, and the appearance and characteristics of the spray showed no obvious change. Conclusion :The stability of the compound Lidocaine hydrochloride spray is satisfactory.
出处 《黑龙江医药科学》 2007年第6期31-32,共2页 Heilongjiang Medicine and Pharmacy
基金 江苏省盐城市2004年第二批医学科技发展计划项目(编号:YK2004254)
关键词 复方利多卡因喷雾剂 稳定性 compound Lidocaine hydrochloride spray stability
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  • 1李家泰.临床药理学[M].北京:人民卫生出版社,1996.873
  • 2YANG DZ,MA YN.The evaluation and treatments of premature ejaculation[J].Chinese clinical physician,2000,28(8):20-21.Chinese
  • 3Diagnosic Criteria from DSM-Ⅳ.American Psychiatric Association[J].Whoshington,DC.1994.
  • 4YUAN YM,XING ZC,JING TY,et al.The multidimensional evaluaion on the patients with premature ejaculation by Chinese sex function evaluate table of the patients with premature ejaculation[J].Chinese journal of andrology,2003,17(5):302-306.Chinese
  • 5GUO YL.Erectile dysfunction[M].Beijing:Beijing Medical University Press,1999:121.Chinese
  • 6COLPI GM,FANCIULLACCI F,BERETTA G,et al.Evoked sacral potentials in subjects with true premature ejaculation[M].Andrologia,1988,15-17.
  • 7XIN ZC,CHIO YD,RHA KH,et al.Somatosensory evoked potentials in patients with primary premature ejaculation[J].J Urol,1997,158(2):451-455.
  • 8XIN ZC,CHUNG WS,CHOI YD,et al.Penile sensitivity in patients with primary premature ejaculation[J].J Urol,1996,157(3):979-981.
  • 9XIN ZC,CHIO YD,SEONG DH,et al.Sensory evoked potential and effect of SS-cream in premature ejaculation[J].Yonsei Med J,1995,36(5):397-401.
  • 10LI JT.The clinical pharmacology[M].Beijing:.People's Medical Publishing House,1996:873.Chinese

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