颅内中枢神经细胞瘤高场MRI诊断

High-field MRI diagnosis of central neurocytoma

目的:分析颅内中枢神经细胞瘤的MRI影像学特征,为临床诊疗提供影像学依据。方法:回顾性分析12例中枢神经细胞瘤的MRI表现及临床诊疗过程,并结合文献分析其临床影像学特征。结果:12例中枢神经细胞瘤中,10例位于侧脑室内前2/3,1例位于右侧额叶,1例位于第四脑室内。在MRIT1WI上,中枢神经细胞瘤呈等信号或低信号,T2WI上呈稍高信号,可见明显血管流空影。10例病例均行肿瘤全切术,2例行肿瘤次全切除术;9例病例术后均行放疗。随访1年,无复发。结论:中枢神经细胞瘤主要位于侧脑室内,也可位于脑实质或第四脑室内。侧脑室内前2/3肿瘤,尤其是透明隔的肿瘤,应考虑中枢神经细胞瘤的可能,MRI有助于鉴别诊断。

Objective：To analyze the features of central neurocytoma in magnetic resonance imaging （MRI） and provide evidence for MRI-based clinical diagnosis and treatment of central neurocytoma. Methods： The images of 12 patients with central neurocytoma obtained from MRI scanning were reviewed in relation to their clinical diagnosis and treatment, and the imaging features of this disease were analyzed with reference to related literature. Results：Ten central neurocytomas occurred in the anterior 2/3 of the lateral ventricle, 1 in the right frontal lobe,and 1 in the fourth ventricle. Typically, MRI T1 WI presented isotense or hypotense signals for this disease and T2 WI presented slightly hypertense signals,with obvious blood vessel flow-void sign. Radical resection of the central neurocytomas was performed in 10 cases,subtotal resection in 2 cases,and radiotherapy was administered in 9 of the cases after operation. No recurrence of the tumor was found during the one-year follow-up. Conclusion：Central neurocytomas often involve the lateral ventricle, but may also occur in the brain parenchyma or the fourth ventricle. Central neurocytomas can be suspected for tumors involving the anterior 2/3 of the lateral ventricle,especially the septum pellucidum,and MRI is helpful for a differential diagnosis.