电影相位对比MRI肝硬化上消化道出血门静脉血流动力学研究

Hemodynamic Changes by PC MRI in Variceal Hemorrhage of Patients with Portal Hypertension

目的:采用电影相位对比MRI定量肝硬化门静脉血流,评价其与消化道出血的关系。方法:对49例门静脉高压症患者行电影相位对比MRI门静脉血流定量测量,依照病史分为出血组31例,无出血组18例;另选对照组19例。结果:门静脉高压出血组及未出血组门静脉主干截面积与正常组比较均显示明显增大(P<0.05),肝硬化出血组门静脉流速较未出血组流速增高,但较正常对照组减低,该差异无统计学意义(P>0.05),肝硬化出血组门静脉血流量明显增高,与正常组及肝硬化未出血组比较,差别具有统计学意义(P<0.05)。结论:电影相位对比MRI能客观反映门静脉血流动力学改变。

Objective：To investigate hemodynamic changes in variceal hemorrhage of patients with portal hypertension. Methods： A total of 49 patients were divided into 2 groups. 18 patients in group A were without history of bleeding and 31 in group B were with twice bleeding or with varices. 19 people were in the normal control group. The portal vein hemodynamic changes were measured by Cine PC MRI. Results：The section areas of main portal vein in two portal vein hypertention groups were larger than that in the normal control group （P〈0. 05）,the VPV of patients with variceal hemorrhage was lower than that in the controls and higher than that without variceal hemorrhage （P〉0.05）,The Qpv of patients with variceal hemorrhage was much higher than those in patients without homorrhage and controls （P〈0. 05）. Conclusion： Hemodynamic changes of portal hypertention in pations with cirrhosis can be correctly measured by Cine PC MRI.