2型糖尿病患者IRS-2基因型对运动易感性差异的研究

Study on the susceptibility difference in response to exercise in receptor substrate-2 gene polymorphism of type 2 diabetes

研究西安市汉族人群中2型糖尿病患者IRS-2基因密码子1057g/a多态性与运动易感性间的相关性.PCR-RFLP的方法检测IRS-2基因密码子1057g/a多态性后,随机分3组:gg、ga和aa基因型组,经12周的太极拳运动锻炼后发现,aa基因型组对运动的易感性最高,反映糖尿病情改善的主要指标均发生了良好的改变.发现西安市汉族人群中不同2型糖尿病患者IRS-2基因型对运动的易感性存在着明显差异,aa基因型组患者的运动易感性高于其他基因型.

Study on the susceptibility difference in response to exercise in receptor substrate-2 gene polymorphism of type 2 diabetes in Chinese Han population in Xian. Type 2 diabetic cases were divided into three groups as ga,gg and aa groups after the methods of PCR-RFLP test. The aa geno type has higher susceptibility in response to 12 weeks＇ Taijiquan exercise, and the main index changed obviously showing the good treatment compared with other two groups. The susceptibility is different in response to exercise in IRS-2 gene polymorphism of type 2 diabetes in Chinese Han population in Xi＇an. The aa geno type of IRS-2 gene has higher susceptibility in response to exercise.