动脉粥样硬化性肾动脉狭窄的研究进展

Research Progress of Atherosclerotic Renal Artery Stenosis

动脉粥样硬化性肾动脉狭窄(ARAS)是一慢性缺血进展性肾病(CIRD),是中老年人终末期肾病(ESRD)常见原因之一。在冠状动脉粥样硬化性心脏病、充血性心力衰竭、周围血管病和慢性肾衰竭人群中具有较高的患病率。临床上常表现难治性高血压、肾功能不全和肺水肿,部分患者可无症状直至出现ESRD,容易误诊。经肾血管介入治疗或外科手术治疗多数患者病情可缓解,但预后往往较差。充分认识和重视引起的慢性肾脏病,早期诊断,及时治疗,更好地保护肾功能,减少和延缓ESRD的发生和进展,改善预后。

Atheresclerotic renal artery stenesis（ARAS） is a chronic ischemic renal disease（CIRD）, which is one of the common causes of ESRD. It also has higher morbidity rate in people with coronary atheroselerotic herat disease, congestive cardiac failure, peripheral angiopathy, chronic renal failure. Its clinical manifestation are refractory hypertension,renal inadequacy and pneumonedema. Partial people have no clinical manifestation until the occurrence of ESRD, which is easy to be misdiagnosed. Pathological condition of most of people maybe relieved by interventional therapy of vessel of kidney or surgery, but the prognosis is pften poor. To recognize and pay more attention of this chronic renal diseases, as well as to diagnose earlier and treat in time can reduce or postpone the occurrence and developmont of ESRD and promote the prognosis.