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水溶性低分子质量壳聚糖致鼠脱毛的毒理性研究 被引量:9

Study on Toxicology of Oligochitosan on Hair Removal in Mouse Model
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摘要 通过对水溶性低分子质量壳聚糖致鼠脱毛的毒理性研究,评价低分子质量壳聚糖的潜在毒性.实验包括致小鼠脱毛观察、生理指标检测、组织切片等.结果表明,水溶性低分子质量壳聚糖致鼠脱毛与肾毒性相关. The result of hair removal after subcutaneous injection of oligochitosan in mice and rats was studied in this paper, using the observation of hair removal and tissue slices and the detection of hematological parameters. It is shown from the determination results that oligochitosan has renal toxicity.
出处 《天津科技大学学报》 CAS 2007年第4期20-23,共4页 Journal of Tianjin University of Science & Technology
基金 人事部中国博士后基金资助项目(20060400709) 天津科技大学人才引进基金资助项目(2006403)
关键词 低分子质量壳聚糖 肾毒性 氨基糖苷类抗生素 安全性 oligochitosan renal toxicity aminoglycoside antibiotics safety
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参考文献8

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