维生素D与跌倒

Vitamin D and Falls

老年人容易发生跌倒,在社区居住的>65岁的老年人中每年有30%～40%发生跌倒。与跌倒相关的并发症严重影响了老年人的生活质量。既往的荟萃分析得出:维生素D可以使跌倒的发生率降低22%,而最近的一些研究却得出了不同的结论。文章阐述了维生素D减少跌倒发生的可能机制,重点分析了维生素D与肌力及平衡能力的关系。对近年有关维生素D和跌倒的临床试验进行综述,旨在进一步明确维生素D预防跌倒的意义。

Elder is liable to falls,among which about 30% ～40% elder above 65 years old have falls in community resident every year.Complication related to falls have greatly affected quality of life of these elders.The past meta-analysis of 5 randomized controlled trials suggested that vitamin D willl decre ase occurrence rate of falls about 22%,while recent researches showed diffe rent conclusion.This article reviews possible mechanism of Vitamin D in reduc ing falls,especially analyze the relationship between Vitamin D and myodynamia as well as balance ability.This article also reviews clinical trial abo ut Vitamin D and falls in order to identify the significance of VitaminD in prev enting falls.