摘要
建立了HPLC法测定福多司坦颗粒含量和有关物质。用C18色谱柱,甲醇-0.05mol/L戊烷磺酸钠溶液(pH2.0)(10∶90)为流动相,检测波长205nm。福多司坦在60～300μg/ml浓度范围内线性关系良好,方法平均回收率为99.7%,RSD为0.40%。
A HPLC method was established for the determination of fudosteine granules and its related substances. A C18 column was used, with the mobile phase of methanol-0.05mol/L sodium pentane sulfonate solution （pH 2.0） （10 ： 90）, at the detection wavelength of 205nm. The calibration curve was linear in the concentration range of 60-300μg/ml. The average recovery was 99.7 % with RSD of 0.40 %.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2007年第12期872-874,共3页
Chinese Journal of Pharmaceuticals
