期刊文献+

药物蛋白质组学的技术进展 被引量:1

Advance in Pharmacoproteomics Technology
下载PDF
导出
摘要 蛋白质组学(包括表达蛋白质组学和功能蛋白质组学)作为功能基因组学的一个分支在药物研发过程中起着极其重要的作用,而药物蛋白质组学的发展依赖于其技术的不断更新.论述了药物蛋白质组学技术在不同领域的应用进展,从一个崭新的角度展现了药物蛋白质组学发展的巨大潜力. Proteomics which includes expresing proteomics and functional proteomics plays a vital role in drug development as a branch of functional genomics and phannacoproteomics is being improved by the renovation of proteomics technology. This paper reveals the great development potential of pharmacoproteomics from a brand-new aspect, based on the advance and application of pharmacopmteomics technologies in different foreign fields.
作者 罗灿 刘冰花
出处 《成都大学学报(自然科学版)》 2007年第4期272-276,共5页 Journal of Chengdu University(Natural Science Edition)
关键词 蛋白质组学 药物蛋白质组学 药物研发 protecmics pharmacoproteomics drug development
  • 相关文献

参考文献24

  • 1Klein E, Klein J B, Thongboonkerd V. Two dimension algel electrophoresis : a fundamental tool for expression proteomics studies [J]. Proteomics in Nephrology,2004(141) :25 - 39.
  • 2Steiner S,Gatlin C L,Lennon J J,et al. Cholesterol biosynthesis regulation and protein changes in rat liver following treatment with fluvastatin [ J]. Toxicol Lett,2001,120(1 - 3) :369 - 377.
  • 3Steiner S, Gatlin C L, Lennon J J,et al. Proteomics to display lovastatin-induced protein and pathway regulation in rat liver [ J ]. Electrophoresis, 2000 (21 ) : 2129 - 2137.
  • 4Sanchez J C, Corthals G L,Denis F. Biomedical Applications of Proteomics [ M]. NewYork: Wiley-VCH, 2004.
  • 5Charlwood J,Skehel M J,King M, et al. Proteomic analysis of rat kidney cortex following treatment with gentamicin [ J ]. J Proteome Res, 2002( 1 ) :73 - 82.
  • 6Ostrowski L E, Blackburn K, Radde K M, et al. A proteomic analysis of human cilia : identification of novel components [ J ]. Mol Cell Proteomics,2002( 1 ) :451 - 465.
  • 7Falkner, Jayson, Andrews, et al. Fast tandem mass spectrabased protein identification regardless of the number of spectra or potential modifications examined [ J ]. Bioinformatics, 2005, 21 (10) :2177 - 2184.
  • 8Anderson N L, Anderson N G. The human plasma proteome: history, character, and diagnostic prospects [J]. Mol Cell Proteomics, 2002( 1 ) : 845 - 867.
  • 9Florens L,Washburn M P, Raine J D, et al. A proteomic view of the Plasmodium falciparum life cycle [J]. Nature, 2002(419) : 520 - 526.
  • 10W Andy Tao,Ruedi Aebersold. Advances in quantitative proteomics via stable isotope tagging and mass spectrometry[J]. Current Opinion In Biotechnology, 2003 (14) : 110 - 118.

同被引文献14

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部