340例脑瘫患儿脑干听觉诱发电位的临床分析

Clinical Analysis on Brain Auditory Evoked Potential in 340 Children with Cerebral Palsy

目的:探讨脑瘫患儿脑干听觉诱发电位(BAEP)与脑瘫类型、合并损伤及高危因素的关系。方法:采用神经肌电诱发电位仪对340例脑瘫患儿行BAEP检查和分析。结果:脑瘫患儿BAEP异常率为22.9%,并发智力低下的异常率明显高于无智力低下的患儿(P<0.01);高危因素中宫内感染、黄疸和颅内出血与BAEP异常发生有密切关系,其中黄疸和宫内感染是高度危险因素;脑瘫并发听神经通路损伤的发生率较普遍,其中混合型和手足徐动型发生率更高。结论:宫内感染和病理性黄疸是脑瘫患儿听神经通路损伤的高度危险因素,BAEP应作为脑瘫患儿常规检查。

Objective： To study the relationship between brain auditory evoked potential （BAEP） and the classification, associated disorders and high risk factors of cerebral palsy （CP） in children. Methods： 340 children with CP were selected and analyzed after tested with BAEP. Resuhs： The BAEP abnormal rate among children with CP was 22.9% . In the CP children associated with mental retardation （MR）, the BAEP abnormal rate was significantly higher than in those without MR （P〈0. 01）. The abnormal BAEP was closely related with intrauterine infection, jaundice and intracranial hemorrhage. Among the risk factors, Jaundice and intraeranial hemorrhage were the high risk factors. The children with CP were commonly accompanied by auditory nerve pathway disorder, which was related with clinical classification. The rate of auditory nerve pathway disorder was high in mixed and athetotic CP. Conclusion： Intrauterine infection and pathologic jaundice are high risk factors for the auditory nerve pathway disorder in CP. BAEP should be a regular test in CP.