结直肠癌根治术后单纯性肺转移60例临床病例分析

Lung metastasis after resection of colorectal cancer,a report of 60 cases

目的:结直肠癌患者根治术后大约有50%会发生远处转移,最常见的转移部位是肝,其次是肺,本文旨在探讨结直肠癌根治术后肺转移的特点、治疗效果和影响预后的因素。方法:随访1967年至2002年间的结直肠癌根治术后发生单纯性肺转移的60例病例,对其临床资料进行回顾性分析和总结。结果:自原发灶切除术后全组病例中位生存时间37个月,其中有15例行转移灶的切除手术,中位生存51个月;其余45例行非手术治疗,中位生存34个月;转移瘤大于3个组生中位生存时间30月,转移瘤小于等于3个组中位生存时间43个月。患者的总生存率可能和是否手术、转移灶的个数有关,而年龄、性别、原发灶病理类型、分期、转移灶大小对生存率无明显影响。结论:结直肠癌根治术后单纯性肺转移的积极治疗是有效的,手术及转移灶个数可能是影响治疗效果的因素。

Objective： This study was to investigate the features, treatments and prognostic factors of patients with lung metastatic diseases after resection of colorectal cancer. Methods： Clinical data of 60 patients who suffered lung metastatic diseases after received radical resection of colorectal cancer in 1967-2002, were retrospectively analyzed. Results： The median survival time after the primary disease operation is 37 months .The median survival time of 15 cases who had received lung operation is 51 months, the other patients＇ is 34 months. The median survival time of patients with more than 3 metastatic diseases in the lung is 30 months, the other patients＇ is 43 months. The overall survival time was probably associated with operations of the lung and the number of metastatic diseases, and the other factors were of no significance. Conclusion： The active treatment for the lung metastasis after colorectal cancer operation is effective. The operation and the number of metastasis may be the factors that can influence the patients＇ prognosis.