摘要
目的:探讨影响子宫肉瘤生存率的因素。方法:对101例子宫肉瘤临床病例资料,使用COX比例风险模型及Logr-nank检验方法,分别进行多因素及单因素分析、结果:COX模型多因素预后分析表明,对子宫肉瘤患者影响其生存率的主要因素是临床分期、病理分类、绝经情况,子宫大小是一项次要因素。Ⅰ,Ⅱ期的预测5年生存率为58%,Ⅲ期为34%,Ⅳ期为23%。平滑肌肉瘤的5年生存率为45%,中胚叶混合肉瘤为34%,宫内膜间质肉瘤为28.9%。结论:子宫肉瘤患者影响生存期的主要因素是临床分期、病理分类、绝经情况三项,子宫大小是一项次要因素。
Purpose: To evaluate the significant prognostic factors related to survival in patients with uterine sarcoma, Method:Analysis of prognostic factors was performed by COX'S proportional hazard model and logank logarithmie series test method in 101 cases with uterine sarcoma. Results: The 5-year survival rate was 58% in clinical stage Ⅰ,Ⅱ, 34% in clinical stage Ⅲ, 23% in clinical stage Ⅳ. The 5-year survival rate 45% in leiomyosarcoma, 34% in mesodermal haxed sarcoma, 72. 5 % in endometrial stromal sarcoma. Conclusion: The major significant prognostic factors related to survival are clinical staging, histopathologic type and menopausal status. The size of uterus is a minor factor.