期刊文献+

乳腺癌保乳综合治疗98例临床分析 被引量:1

下载PDF
导出
摘要 目的:研究保乳手术在0、Ⅰ、Ⅱ期乳腺癌中的治疗效果。方法:98例0、Ⅰ、Ⅱ期乳腺癌患者术前常规行钼靶检查,术前在超声引导下或直接粗针穿刺进行病理及免疫组化检查。除初期5例外,其他病例均行术前新辅助化疗至少2疗程。全部行了保乳手术,切除肿瘤周围约1~1.5cm的正常组织,达到切缘阴性。肿瘤位于外上象限且近边缘部时,起初采用与腋部同一切口,后改用双切口。从2005年1月起,若前哨淋巴结阴性,则不做腋窝清扫。术后给予化疗、放疗及内分泌治疗(激素受体阳性者)。结果:本组保乳率为26.8%(98/365)。随访4月~36月,无1例局部复发或死亡,出现肝及肺转移2例。保乳的美容效果满意率为84.3%。结论:保乳手术适宜0、Ⅰ、Ⅱ期乳腺癌,可以取得良好的生存率、局部控制率和美容效果,是早期乳腺癌治疗的首先术式。
出处 《岭南急诊医学杂志》 2007年第6期458-459,共2页 Lingnan Journal of Emergency Medicine
  • 相关文献

参考文献4

二级参考文献38

  • 1[1]Arriagada R, Le MG, Rochard F, et al. Conservative treatment versus mastectomy in early breast cancer: patterns of failure with 15 years of follow-up data. Institute Gustave-Roussy Breast Cancer Group[J]. J Clin Oncol, 1996,14(5): 1558-1564.
  • 2[2]Van Dongen JA, Voogd AC, Fentiman IS, et al. Long term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial [J]. J Natl Cancer Iust, 2000,92(14):1143-1150.
  • 3[3]Kokubo M, Mitsumori M, Ishikura S, et al. Results of breastconserving therapy for early stage breast cancer [J]. Am J Clin Oncol, 2000,23(5):499-505.
  • 4[4]van der Hage JA, van der Velde CJH, Julien JP, et al. Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for Research and Treatment of Cancer Trial 10902[J]. J Clin Oncol, 2001,19(22): 4224-4237.
  • 5[5]Veronesi U, Saccozzi R, Del Vecchio M, et al. Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast [J]. N Engl J Med,1981,305(1):6-11.
  • 6[6]Fisher B, Bauer M, Margolese R, et al. Five-year results of a randomized clinical trial comparing totol mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer [J]. N Engl J Med, 1985,312(11) :665-673.
  • 7[7]Hiraoka M, Kodama H, Mitsumori M, et al. Preliminary results of quadrantectomy and radiation therapy for breast cancer [J].Breast Cancer,1994,1(2): 117-122.
  • 8[8]Fowble B, Solin LJ, Schultz DJ, et al. Breast recurrence following conservative surgery and radiation: pattern of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment[J]. Int J Radiat Oncol Biol Phys, 1990,19(4) :833-842.
  • 9[9]Neuschatz AC, Dipetrillo T, Safaii H, et al. Long-term follow-up of a prospective policy of margin-directed radiation dose escalation in breast-conserving therapy[J]. Cancer, 2003,97(1) :30-39.
  • 10[10]Fisher B, Wickerham DL, Deutsch M, et al. Breast tumor recurrence following lumpectomy with and without breast irradiation :an overview of recent NSABP findings[J]. Semin Surg Oncol,1992,8(3) 153-160.

共引文献48

同被引文献5

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部