摘要
目的建立多种喹诺酮类(FQs)药物同时检测的高效液相色谱方法,建立水产品中(FQs)药物残留提取的前处理方法。方法研究水产品中喹诺酮类药物检测的最佳提取条件,液相色谱条件和荧光检测参数等。结果在该实验条件下,7种FQs类药物检测线性范围0.01～0.50mg/L(沙拉沙星0.10～5.0mg/l),最低检出限0.08～0.36μg/kg,变异系数1.5%～8.6%,样品加标回收率64.0%～93.4%。结论该方法能同时检测水产品中多种(FQs)药物残留,简单、快速、精密度较好、准确灵敏度较高,结果较满意。
[ Objective] To establish high performance chromatography for the simultaneous determination of multiple fluoroquinolone residues in aquatic products. [ Methods] The optimal condition of detecting fluoroquinolone residues in the aquatic products, liquid chromatographic condition and fluorescence detection parameter were studies. [ Results ] Under this experimental condition, the line- ar range of 7 kinds of fluoroquinolone drugs was 0.01 ~ 0.50mg/L; the detection limit was 0.08-0. 36 μg/kg; RSD ranged from 1. 5% to 8.6% ; the labeled recovery rate of the samples was 64.0% ～ 93.4%. [ Conclusion] This method is simple, rapid, accu- rate and precise in the simultaneous determination of multiple fluoroquinolone residues in aquatic products.
出处
《职业与健康》
CAS
2008年第2期119-121,共3页
Occupation and Health
关键词
水产品
氟喹诺酮类
残留
高效液相色谱
Aquatic products
Fluoroquinolone
Residue
High performance chromatography
Determination
