川芎嗪治疗重症急性胰腺炎的研究

Study of Ligustrazine on severe acute pancreatitis

目的探讨川芎嗪注射液治疗重症急性胰腺炎(SAP)的疗效。方法随机把SAP患者分为2组,均予常规治疗,在此基础上观察组加用川芎嗪注射液治疗,观察2组APACHEⅡ评分、治疗有效率、饮食恢复正常时间、血尿淀粉酶恢复正常时间和住院时间。结果观察组在APACHEⅡ评分、治疗有效率、饮食恢复正常时间、血尿淀粉酶恢复正常时间和住院时间方面均优于对照组。结论川芎嗪注射液治疗重症急性胰腺炎疗效明显。

Objective It is to explore the therapeutical effect of Ligustrazine injection on severe acute pancreatitis（SAP）. Methods Patients with SAP were randomly divided into 2 groups. Both the two groups were given normal treatment. Patients in observation group were added with Ligustrazine injection. APACHE Ⅱ scores, effective rate, the time of reverting to eat, the time of amylase in blood and urinary to revert and the time of staying in hospital in the two groups were compared with each other. Results Comparing with the contrast group, the therapeutic effect of SAP in observation group was better in APACHE Ⅱ score, effective rate, the time of reverting to eat, the time of amylase in blood and urinary to revert and the time of staying in hospital. Conclusion Ligustrazine injection has a obvious therapeutic effect on SAP.