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儿童传染性单核细胞增多症92例临床分析 被引量:2

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摘要 目的对儿童传染性单核细胞增多症的临床表现及实验室检查进行总结分析,以提高本病的诊断治疗水平。方法对2005年1月~2006年12月我院收治的92例传染性单核细胞增多症进行回顾性临床分析。结果本病多见于学龄前儿童,临床表现多样,发热(96.7%)、咽峡炎(79.3%)、淋巴结肿大(70.7%)、肝大(56.5%)、脾大(52.2%)、皮疹(18.5%)、眼睑浮肿(44.6%)、鼻塞(22.8%)以及呼吸、循环、泌尿、中枢神经系统受累症状;实验室检查外周血异型淋巴细胞增高(>10%占63.0%,3~9%占20.7%),EB病毒衣壳抗原IgM(VCA-IgM)阳性(84.8%)。结论本病是全身性疾病,临床表现多样,不典型病例多,易误诊、漏诊,需提高对本病的认识与重视,外周血异型淋巴细胞增高、VCA-IgM阳性有助确诊。
出处 《海南医学》 CAS 2008年第1期94-95,共2页 Hainan Medical Journal
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  • 1张之南.血液病诊断及疗效标准[M].天津科学技术出版社,1992.187.
  • 2胡亚美 江载美.实用儿科学7版[M].北京:人民卫生出版社,2002.824.
  • 3吴瑞萍 胡亚美 江载芳.诸福棠实用儿科学(第7版)[M].北京:人民卫生出版社,2002.2170.
  • 4Pitetti RD, Laus S, Wadowsky RM. Clinical evaluation of a quantitative real time polymerase chain reaction assay for diagnosis of primary Epstein - Barr virus infection in children. Pediatr Infect Dis J, 2003; 22(8):736.
  • 5Cohen JI. Benign and malignant Epstein - Barr virus - associated B - cell lymphoproliferative diseases. Semin Hematol,2003;40(2): 116.
  • 6Bharadwaj M, Moss DJ. Epstein- Barr virus vaccine: a cytotxic T- cell - based approach. Expert Rev Vaccine, 2002; 1(4) :467.
  • 7Charles PG. Infectious Mononucleosis. Aust Fam Physician.2003Oct;32(10) :785.
  • 8Chan CW, Chiang Ak,Chan KH,et al. Epstein- Barr virusassociated infectious mononucleosis Chinese children. Pediatr Infect Dis J, 2003; 22(11):974.
  • 9Macsween KF, Crawford DH. Epstein - Barr virus - recent advances. Lancet Infect Dis.2003;3(3): 131.
  • 10Jain V, Singhi S, Desai RV. Infectious mononucleosis presenting as upper airway obstruction. Indian J Chest Dis allied Sci,2003;45(2): 135.

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  • 1杨娜娜,王娟,杜立新.细胞永生化的研究进展[J].中国畜牧兽医,2005,32(1):37-39. 被引量:10
  • 2Gregorovic G,Bosshard R,Karstegl C E,et al. Cellular gene expression that correlates with EBER expression in Epstein-Barr vires-infected lymphoblastoid cell lines [ J ]. J Viro1,2011,85 ( 7 ) :3535 -3545.
  • 3Horiuchi K, Mishima K, Ohsawa M, et al. Carcinoma of stomach and breast with lymphoid stroma: localisation of Epstein-Barr virus [ J ]. J Clin Pathol, 1994,47 (6) :538-540.
  • 4Labrecque L G, Barnes D M, Fentiman I S, et al. Epstein-Barr virus in epithelial cell Iumors:a breast cancer study[ J ]. Cancer, 1995,55( 1 ) :3945.
  • 5Bonnet M, Guinebretiere J, Kremmer E, et al. Detection of Epstein- Barr virus in iuvasive breast cancers [ J ]. J Nail Caneer InsI, 1999, 91 : 1376-1381.
  • 6Chu P G, Chang K L, Chen Y Y, et al. No significant association of Epstein-Ban" virus infection with invasive breast carcinoma [J]. J Pathology,2001,159(2) :571-578.
  • 7Fina F,Romain S,Ouafik L,et al. Frequency and genome load of Epstein-Barr virus in 509 breast cancers from different geographical areas [ J ]. Br J Cancer,2001,84 (6) :783-790.
  • 8McCall S A, Lichy J H, Bijwaard K E, et al. Epstein-Barr virus detection in ductal earcinoma of the breast [ J ]. J Natl Cancer Inst,2001,93 (2) : 148-150.
  • 9Perkins R S, Sahm K, Marando C, et al. Analysis of Epstein-Barr virus reservoirs in paired blood and breast cancer primary biopsy specimens by real-time PCR [ J ]. Breast Cancer Rcs, 2006,8 (6) :R70.
  • 10Trabelsi A, Rammeh S, Stita W, et al. Detection of Epstein-Barr virus in breast cancers with lymphoid stroma[ J]. Ann Biol Clin (Paris) ,2008,66 ( 1 ) :59-62.

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