摘要
目的探讨乙型肝炎病毒携带者肺移植术后肝功能变化及可能对长期生存的影响。方法对本院1名患COPD及陈旧性肺结核的乙肝病毒携带者肺移植术后的肺功能及肝功能变化进行观察分析。结果术后2年8个月患者肺功能良好,但在保肝治疗下仍出现病毒性肝炎活动,且肝功能随着患者治疗措施的改变而有所恶化。结论乙肝病毒引发病毒性肝炎可能加重肺移植患者肝功能恶化,环孢素A代替FK506及抗结核药物等治疗可加重肝脏损伤。
Objective To study the effects of HBV on the patient＇s liver function and survival. Methods The HBsAg positive COPD and lung tuberculosis patient received right lung transplantation was followed up to observe the changes of lung function and liver function. Results The patient＇s lung function was good, while his liver function deteriorated and viral hepatitis was detected after the transplantation. Conclusion HBV initiates viral hepatitis and enhances deterioration of patient＇s liver function. CsA not FKS06,and antituberculosis therapy can aggravate liver damage.
出处
《临床肺科杂志》
2008年第1期11-12,共2页
Journal of Clinical Pulmonary Medicine
关键词
乙肝病毒
肺移植
肝功能
免疫抑制剂
结核
HBV
Lung transplantation
Liver function
immunosuppressant
tuberculosis
