我院住院患者真菌感染情况回顾性分析

Retrospective analysis of hospital-acquired mycotic infection in our hospital

目的探讨医院真菌感染的流行情况、危险因素、治疗与预后的关系。方法回顾性分析我院住院患者中237例真菌感染的临床资料。结果住院患者真菌感染呈逐年上升趋势,危险因素为:老年患者、使用广谱抗菌药物及糖皮质激素、有恶性肿瘤、慢性阻塞性肺疾病、糖尿病等慢性基础疾病,营养状况差。未及时抗真菌治疗患者病死率高。结论合理使用抗菌药物及糖皮质激素,以及早期诊断和及时抗真菌治疗,加强营养支持治疗是降低住院患者真菌感染并降低病死率的重要措施。

Objective To discuss the hospital-acquired mycotic infection, its spread condition, risk factor, and related healing and prognostic conditions. Methods Clinical data of 237 in-patients who had myucotic infection in our hospital were analyzed. Results Mycotic infection in in-patients showed an increased tendency yearly. The risk factor included old age, use of broad-spectrum antibacterials glucoeorticoid, having malignant tumor or COPD, diabetes or other chronic base disease, poor nutritional status etc. The fatality rate was high among those without timely treatment of mycetes. Conclusion It is important to carefully avoid the risk factors in order to cut down hospital-acquired mycotic infection, to reduce case - fatality rate.