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硬膜外芬太尼加左旋布比卡因超前镇痛在全麻中的应用 被引量:2

Epidural administration of fentanyl plus levo bupivacaine for preanalgesia of general anesthesia
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摘要 目的观察硬膜外超前镇痛对全麻的影响及合理的用药方案。方法60例手术患者分为3组,每组各20例。硬膜外穿刺后经硬膜外导管注入芬太尼50μg(Ⅰ组),左旋布比卡因加芬太尼超前镇痛组(Ⅱ组)、左旋布比卡因加芬太尼术后镇痛组(Ⅲ组),术后均采用硬膜外自控镇痛(PCEA)。观察术后视觉模拟(VAS)评分和PCA次数,并比较瑞芬太尼及维库溴铵的用量和拔管时问(停用全麻药至拔除导管)以及苏醒质量。结果瑞芬太尼及维库溴铵的用量、拔管时间、苏醒时期兴奋躁动发生率Ⅲ组>Ⅰ组>Ⅱ组;3组患者镇痛效果、镇痛用药量、24小时PCA总按压次数Ⅰ组>Ⅲ组>Ⅱ组,3组比较差异有显著性意义(P<0.01)。结论硬膜外使用小剂量的芬太尼加左旋布比卡因硬膜外超前镇痛,患者术后苏醒不受影响,而且减少了恢复期兴奋的发生,效果满意,值得临床推广。
出处 《实用医院临床杂志》 2008年第1期53-54,共2页 Practical Journal of Clinical Medicine
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