期刊文献+

维生素D及其类似物治疗视网膜母细胞瘤的研究进展 被引量:2

Vitamin D and its analogs in treatment of retinoblastoma
下载PDF
导出
摘要 视网膜母细胞瘤的维生素D疗法是一种非诱变的化学疗法。本文综述了20a来,国内外许多学者对维生素D及其类似物治疗视网膜母细胞瘤进行的广泛研究,其抗癌作用已经得到肯定。现分别从维生素D及其类似物治疗视网膜母细胞瘤的分子机制、毒副作用及其应用前景方面进行综述。 Vitamin D therapy is non-mutagenic in the chemotherapy of retinoblastoma. Its anti-tumor effect is confirmed. This article reviews extensive researches from the areas of molecular mechanisms, toxicity and application prospects on vitamin D and its analogs in the treatment of retinoblastoma studied by foreign and domestic scholars in the past 20 years.
出处 《眼科新进展》 CAS 2007年第12期949-952,共4页 Recent Advances in Ophthalmology
关键词 维生素D 维生素D受体 视网膜母细胞瘤 vitamin D vitamin D receptor retinoblastoma
  • 相关文献

参考文献21

  • 1Albert DM, Plum LA, Yang W, Marcet M, Lindstrom MJ, Claqett-Dame M, et al. Responsiveness of human retinoblastoma and neuroblastoma models to a non-calcemic 19-nor vitamin D analog[ J]. J Mol Biol 2005 ;97 ( 1 ) : 165-172.
  • 2宋爽,张军军.视网膜母细胞瘤的治疗进展[J].四川医学,2004,25(5):597-598. 被引量:4
  • 3Wagner N, Wagner KD, Schlcy G, Badiali L, Theres H, Scholz H. 1,25-dihydroxyvitamin D3 -induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax[ J]. Exp Eye Res 2003 ;77 ( 1 ) : 1-9.
  • 4Saulenas AM,Cohen SM,Key LL,Winter C,Albert DM. Vitamin D and retinoblastoma. The presence of receptors and inhibition of growth in vitro [ J]. Arch Ophthalmol 1988 ;106(4) :533-535.
  • 5黄克锋,李会庆.维生素D受体基因多态性肿瘤易感性研究进展[J].中国公共卫生,2005,21(3):373-374. 被引量:1
  • 6Brown AO, Dusso A, Slatopolsky E. Vitamin D [ J ]. Am d Physiol 1999;277(2 Pt2) :157-175.
  • 7姚天明,杨靖,张晓辉.维生素D及其衍生物在肿瘤发生与治疗研究中的应用[J].临床军医杂志,2002,30(4):76-78. 被引量:1
  • 8骆文静,陈景元,王文亮.维生素D及其类似物抗肿瘤作用机制[J].国外医学(肿瘤学分册),2004,31(6):425-428. 被引量:7
  • 9Ryhanen S, Jaaskelainen T, Mahonen A, Maenpaa PH. Inhibition of MG-63 cell cycle progression by synthetic vitamill D3 analogs mediated by p27, Cdk2, cyclin E, and the retinoblastoma protein [ J ]. Biochem Pharmacol 2003 ; 66 (3) :495-504.
  • 10Gumireddy K, Ikegaki N, Phillips PC, Sutton IN, Reddy CD. Effect of 20-epi-1 alpha, 25-dihydroxyvitamin D3 on the proliferation of human neuroblastoma: role of cell cycle regulators and the Myc-Id2 pathway[ J]. Biochem Pharm 2003 ;65 ( 12 ) : 1943-55.

二级参考文献44

  • 1李瑾,杨原.维生素D_3促进大鼠胃癌血管新生机制的研究[J].解放军医学杂志,2001,26(8):604-605. 被引量:3
  • 2An Gao Xu Shao Guang Li Ji Hong Liu Ai Hua Gan Research Laboratory of Digestive Disease,Huizhou Central People’s Hospital,Huizhou 516001,Guangdong Province,ChinaDr.An Gao Xu graduated from Guangdong Medical College in 1984.He is an associate physician-in-chief,specializing in the research and treatment of gastrointestinal and liver tumors.He has published 24 papers and 1 book..Function of apoptosis and expression of the proteins Bcl-2,p53 and C-myc in the development of gastric cancer[J].World Journal of Gastroenterology,2001,7(3):403-406. 被引量:91
  • 3[1]Miyamoto,k,Kesterson RA,Yamamoto H,et al.Sturctural or ganization of human vitamin D receptor chroosomal gene and its promoter[J].Mol Endocrinol,1997,11:1165-1179.
  • 4[2]Cadberg C,Polly P.Gene regulation by vitamin D3[J].Crit Rev Eukaryot Gene Exp,1998,8:19-42.
  • 5[3]Hutchinson PE,Osborne JE,Lear JT,et al.Related articles vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma[J].Clin Cancer Res,2000,6(2):498-504.
  • 6[4]Lundin AC,Soderkvist P,Eriksson B,et al.Related Articles Association of breast cancer progression with a vitamin D receptor gene polymorphism,South-East Sweden Breast Cancer Group[J].Cancer Res,1999,59(10):2332-2334.
  • 7[5]Medeiros R,Morais A,Vasconcelos A,et al.The role of vitamin D receptor gene polymorphisms in the susceptibility to prostate cancer of a southern European population[J].Hum Genet,2002,47:413-418.
  • 8[6]Gsur A,Madersbacher S,Haidinger G,et al.Vitamin D receptor gene polymorphism and prostate cancer risk[J].Prostate,2002,51:30-34.
  • 9[7]Habuchi T,Suzuki T,Sasaki R,et al.Association of vitamin D receptor gene polymorphism with prostate cancer and benign prostatic hyperplasia in a Japanese population[J].Cancer Res,2000,60:305-308.
  • 10[8]Habuchi T,Liqing Z,Suzuki T,et al.Related Articles Increased risk of prostate cancer and benign prostatic hyperplasia associated with a CYP17 gene polymorphism with g gene dosage effect[J].Cancer Res,2000,60(20):5710-5713.

共引文献9

同被引文献17

  • 1范列英,仲人前,屠小卿,朱烨,弓长丽,周琳,赵智贤,Ralph Feltens,Thomas Pfeiffer.维生素D受体基因多态性与中国人自身免疫肝病相关性研究[J].中华医学杂志,2003,83(21):1852-1855. 被引量:8
  • 2毛绚霞.维生素D和钙对2型糖尿病的预防作用[J].中国临床营养杂志,2007,15(4):264-268. 被引量:11
  • 3Albert DM, Marcus DM, Gallo JP. The antineoplastid effec of vitamin D in transgenic mice with retinoblastoma [ J ]. Invest Ophthalmol Vis Sci, 1992,33 ( 8 ) :2354 - 2364.
  • 4Wiseman H. Vitamin D is a membrane antioxidant. Ability to inhibit iron - dependent lipid peroxidation in liposomes compared to cholesterol,ergosterol and tamoxifen and relevance to anticancer action[J].FEBS Lett, 1993,326 ( 1 - 3 ) : 285 - 288.
  • 5Cantorna MT,Zhu Y. Vitamin D sttus, 1,25 dihydroxyvitamin D3, and the immune system[J]. Am J Clin Nutr,2004,80(6) :1717 -1720.
  • 6Suzuki T, Sano Y, Kinoshita S. Effects of 1,25 dihydroxyvitamin D3 on Langehans ceil migration and corneal neovascularization in mice [ J ]. Invest Ophthalmol Vis Sci ,2000,41 ( 1 ) : 154 - 158.
  • 7Taverna M J, Sola A, Guyot - Argenton C ,et al. Taq I polymorphism of the vitamin D receptor and risk of severe diabetid retinopathy [ J ]. Dia- betologia,2002,45 ( 3 ) :436 - 442.
  • 8Taverna MJ, Selam JL, Slama G. Association between aprote in poly- morphism in the start codonof the vitamin D receptor gene and severe diabetic retinopathy in C - peptide - negative type 1 diabetes[ J]. J Cli Endo Meta,2005 ,90 :4803 - 4808.
  • 9Payne JF,Ray R,Watson DG,et al. Vitamin D insufficiency in diabetic retinopathy [ J ]. Endocr Prct, 2011,9 ( 22 ) : 1 - 18.
  • 10MattliaC, Knekt P. Serum 25 - hydroxyvitamin D concentration and subsequent risk of type 2 diabetes[ J]. Diabetes Care ,2007,30 ( 10 ) : 2569 - 2570.

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部