多发伤合并多器官功能障碍综合征的危险因素分析

Analysis of risk factors in patients with trauma accompanied by multiple organ dysfunction syndrome

目的探索多发伤患者并发多脏器功能障碍综合征(MODS)的危险因素。方法回顾性分析华中科技大学同济医学院附属同济医院ICU收治的107例多发伤患者的临床资料。将107例多发伤患者分为并发MODS组(n=65例)和非MODS组(n=42例)。分别比较两组多发伤患者的临床和实验室资料:ISS评分、APACHEⅢ评分、GCS评分等的差异。结果两组患者在性别、年龄和休克发生率上差异的无统计学意义,但在休克纠正是否及时、ISS评分、APACHEⅢ评分、GCS评分、血糖和血小板水平上的差异具有统计学意义。Logistic回归分析结果表明,休克纠正是否及时、ISS评分和APACHEⅢ评分是多发伤患者并发MODS的独立危险因素。结论多发伤并发多器官功能障碍综合征的危险因素与休克纠正是否及时、ISS评分和APACHEⅢ评分有关。

Objective To study the risk factors in patients with trauma accompanied by multiple organ dysfunction syndrome. Method The data of 107 patients with trauma in ICU, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, were retrospectively studied. All patients were divided into 2 groups; MODS group and non-MODS group. The clinical and laboratory results, ISS score, APACHEⅢ score and GCS score were studied. Results There were no differences on gender, age and mobility of shock between the two groups. There were significant differences on the treatment of shock, ISS score, APACHEⅢ score, GCS score, the levels of blood sugar and platelet between two groups. The Logistic regression analysis showed the main risk factors were tretment of shock, ISS score and APACHEⅢ score, Conclusions The risk factors in patients with trauma accompanied by multiple organ dysftmction syndrome were the treatment of shock, ISS score and APACHEⅢ score.