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Mel-18在乳腺癌中表达的意义 被引量:4

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摘要 【目的】检测Mel-18在乳腺癌组织标本中的表达状况,探讨Mel-18与各临床病理特征(组织病理类型,临床分期,T分期,肿瘤大小,淋巴结转移状况)的关系。【方法】免疫组化检测63例乳腺癌组织标本中Mel-18的蛋白表达,统计学方法分析Mel-18的表达与临床病理特征(组织病理类型,临床分期,T分期,肿瘤大小,淋巴结转移状况)的关系。【结果】63例乳腺癌标本中仅有19例标本Mel-18阳性(30.15%),阳性信号主要分布在肿瘤细胞核中,Mel-18的表达与患者的淋巴结转移,临床分期呈负相关。【结论】Mel-18可能是乳腺癌预后的一个标志物。
出处 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2006年第B03期27-30,共4页 Journal of Sun Yat-Sen University:Medical Sciences
基金 国家自然科学基金资助项目(30440001 3047066 30570701) 广东省自然基金资助项目(04009427)
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