维持性血液透析患者应用低钙透析液的临床观察

CLINICAL INVESTIGATION OF LOW-CALCIUM DIALYSATE IN MAINTENANCE HEMODIALYSIS PATIENTS

目的:探讨低钙透析液对维持性血液透析患者血钙浓度的影响。方法:进行自身交叉对照研究,将14例维持性血透患者随机分为递降组和递升组,观察先后使用不同钙离子浓度透析液治疗对其血钙浓度的影响。结果:透析液钙离子水平对血透患者的血钙离子浓度有明显影响,使用不同钙离子浓度的透析液,患者的透析前、后血钙水平不同。结论:对于血钙水平正常的血透患者,使用1.25mmol/L钙浓度的透析液能够维持合适的钙平衡,有利于避免高钙血症的发生。

Objective：To investigate the clinical effect of low -calcium dialysate in maintenance hemodialysis （MHD） patients. Methods：In this cross-controlled study, 14 MHD patients were divided into tow group ： decreasing group （used 1.75mmol/L, 1.50mmol/L, 1.25mmol/L dialysate of calcium for one month respectively） and increasing group （ used 1.25mmol/L, 1.50mmol/L, 1.75mmol/L dialysate of calcium for one month respectively）. Serum concentration of calcium was recorded in both groups after each different calcium concentration dialysate. Result： Different dialysate of calcium significantly influenced the levels of serum calcium in hemodialysis patients. Compared with highcalcium dialysate（ 1. 75mmol/L）, the mean concentration of serum calcium in patients with low-calcium dialysate was significantly lower , but was normal range. Conclusion：To the hemodialysis patients with normal serum calcium , low-calcium dialysate（1.25mmol/L） is safe , which may be in favour of avoiding the calcium load .