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半乳凝素-9的研究进展 被引量：1

Advanes in study of galectin-9
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摘要 半乳凝素(galectin)功能多样,galectin-9作为家族成员之一,除了能诱导嗜酸粒细胞聚集和活化外,还介导细胞分化、凋亡、黏附、细胞间聚集、炎症反应的调控和肿瘤转移等。文章将就近年来galectin-9的研究进展进行综述。 Galectins exhibit a variety of biological functions. As a member of galectins, galectin-9 can induce accumulation and activation of eosinophils, it also plays a role in cell differentiation, apoptosis, adhesion, aggregation, modulation of inflammation and metastasis of tumor. This review summarizes the advances in galectin-9 study in these years.
作者 张丰 郑民华
机构地区 上海交通大学医学院瑞金医院上海市微创外科临床医学中心
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2007年第12期1501-1505,共5页 Journal of Shanghai Jiao tong University:Medical Science
关键词 半乳凝素 半乳凝素-9 ecalectin galectin galectin-9 ecalectin
分类号 Q51 [生物学—生物化学]
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参考文献32

  • 1Gray CA, Dunlap KA, Burghardt RC, et al. galectin-15 in ovine uteroplacental tissues [ J ]. Reproduction, 2005, 130 (2) : 231 - 240.
  • 2Wada J, Kanwar YS. Identification and characterization of galeetin- 9, a Novel β-galactoside-binding mammalian lectin [ J ]. J Biol Chem,1997,272(9): 6078 -6086.
  • 3Tureci O, Schmitt H, Fadle N. et al. Molecular definition of a novel human galectin which is immunogenic in patients with hodgkin's disease[J]. J Biol Chem, 1997,272(10) :6416-6422.
  • 4Lipkowitz MS, Leal-Pinto E, Cohen BE, et al. galectin 9 is the sugar-regulated urate transporter/channel UAT [ J ]. Glycoconj J, 2004,19(7 -9) : 491 -498.
  • 5Spitzenberger F. Graessler J. Schroeder HE, et al. Molecular and functional characterization of galectin 9 mRNA isoforms in porcine and human cells and tissues[J]. Biochimic, 2001, 83(9) : 851 -862.
  • 6Sato M, Nishi N, Shoji H, et al. Functional analysis of the carbohydrate recognition domains and a linker peptide of galectin-9 as to eosinophil chemoattractant activity[J]. Glycobiology 2002,3(12), 191 - 197.
  • 7Matsushita N, Nishi N, Seki M, et al. Requirement of divalent galactoside-binding activity of ecalectin/galectin-9 for eosinophil chemoattraction [ J ]. J Biol Chem, 2000, 275 (12) :8355 - 8360.
  • 8Suk K, Hwang DY, Lee MS, et al. Natural autoantibody to galectin-9 in normal human sera[J]. J Clin Immunol, 1999, 19(3) : 158 - 165.
  • 9Menon RP, Hughes RC. Determinants in the N-terminal domains of galectin-3 for secretion by a novel pathway circumventing the endoplasmic reticulum-Golgi complex [ J]. Eur J Biochem, 1999, 264(2) : 569 576.
  • 10Tashiro K, Sakata K, Hirashima M, et al. The regulation of tissue eosinophilia.Ⅲ. In vitro production of eosinophil-directed chemotactic inhibitory factor by T lymphocytes of Freund's complete adjuvant-treated guinea-pigs [ J ]. Immunology, 1985, 55 ( 1 ) : 115 - 124.

同被引文献19

  • 1安宁,王建军.半乳凝素-9蛋白在肺腺癌、鳞癌中的表达及意义[J].中华临床医师杂志（电子版）,2011,5(24):7374-7376. 被引量：3
  • 2许良中,杨文涛.免疫组织化学反应结果的判断标准[J].中国癌症杂志,1996,6(4):229-231. 被引量：1365
  • 3Jaramillo MC,Zhang DD.The emerging role of the Nrf2- Keap 1 signaling pathway in cancer[J].Genes Dev, 2013,27 (20) :2179-2191.
  • 4Qiu Y, Li P,Ji C.Cell Death conversion under hypoxic con- dition in tumor development and therapy[J].Int J Mol Sci, 2015,16(10) :25536-25551.
  • 5Maremanda NG, Roy K, Kanwar RK,et al.Quick chip assay using locked nucleic acid modified epithelial cell adhesion molecule and nucleolin aptamers for the capture of circu- lating tumor cells[J].Biomicrofluidics, 2015,9 (5) : 054110.
  • 6Fujihara S, Mori H, Kobara H,et al.Galectin-9 in cancer therapy[J].Recent Pat Endocr Metab Immune Drug Discov, 2013,7(2) : 130-137.
  • 7International Union Against Cancer.TMN classification of malignant tumours[M].6th ed.NewYork (NY) : Wiley, 2002:102.
  • 8M cSharry B P ,Forbes SK, C ao JZ,e t al.Human cytomegalo virus upregulates expression of the lectin galectin 9 via induction of beta interferon[J].J Virol, 2014,88 (18) : 10990-10994.
  • 9Chart SW, Kallarakkal TG, Abraham MT.Changed expres- sion of E-cadherin and galectin-9 in oral squamous cell carcinomas but lack of potential as prognostic markers[J]. Asian Pac J Cancer Prey,2014,15(5):2145-2152.
  • 10Thijssen VL, Heusschen R, Caers J, et aLGalectin expres- sion in cancer diagnosis and prognosis :a systematic re- view[J].Biochim Biophys Acta,2015,1855(2):235-247.

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上海交通大学学报（医学版）
2007年 第12期

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