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Ⅰ型胶原氨基末端肽在转移性骨肿瘤中的表达和意义 被引量：3

Expression and clinical value of cross-linked type I collagen N-telopeptide in bone metastases
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摘要 骨转移在晚期肿瘤患者中是相当常见的,其发生率占全身转移性肿瘤的第三位,及时和有效的治疗有赖于对骨转移的早期诊断和疗效的评估。现就骨代谢生化指标Ⅰ型胶原氨基末端肽的理化特点、检测方法、在骨转移诊断中的应用、在疾病进展和骨转移疗效评估以及预后评价中的应用作一综述。 Bone metastases, a common problem in advanced cancer patients, occupy the third position of occurrence rate in metastatic cancers. Promptly and effective treatment depends on early diagnosis and evaluation of treatment to bone metastases. This review focuses on biochemical characteristics and detective methods of cross-linked type Ⅰ collagen N-telopeptide, which has clinical value in diagnosis, guiding treatment and prognosis of bone metastases.
作者 周荻 张凤春
机构地区 上海交通大学医学院仁济医院肿瘤科
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2007年第12期1506-1508,1511,共4页 Journal of Shanghai Jiao tong University:Medical Science
关键词 骨生化指标 肿瘤 骨转移 bone biochemical marker tumor bone metastases
分类号 R738.1 [医药卫生—肿瘤]
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参考文献14

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同被引文献14

  • 1王叶,陈健,陈治卿,陈鹭玲,黄春玲,刘莉莉,张忠英.老年妇女血清β-1型胶原C-末端肽与骨密度及骨质疏松症相关性分析[J].中国临床康复,2004,8(29):6304-6304. 被引量：14
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  • 7Lipton A,Cook R,Sand F,et al.Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid[J].Cancer,2008,113:193.
  • 8王立军,傅海平.血清β-胶原特殊序列的测定及初步临床应用[J].检验医学,2007,22(6):633-635. 被引量：9
  • 9R.D.POCKETT,D.CASTELLANO,P.MCEWAN,A.OGLESBY,B.L.BARBER,K.CHUNG.The hospital burden of disease associated with bone metastases and skeletal‐related events in patients with breast cancer, lung cancer, or prostate cancer in Spain[J].European Journal of Cancer Care.2009(6)
  • 10AllanLipton,RichardCook,FredSaad,PierreMajor,PatrickGarnero,EvangelosTerpos,Janet E.Brown,Robert E.Coleman.Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid[J].Cancer.2008(1)

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上海交通大学学报（医学版）
2007年 第12期

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