输血对闭合性肝、脾外伤病人术后感染的影响

EFFECT OF BLOOD TRANSFUSION ON POSTOPERATIVE INFECTION OF LIVER AND SPLEEN CLOSED TRAUMA

目的：探讨输血对闭合性肝、脾外伤病人术后感染的影响，指导合理输血。方法：选择本院2004-01～2006-01期间220例闭合性肝、脾破裂外伤手术病人，其中93例输普通悬浮红细胞，53例输注悬浮去白细胞红细胞，74例未输血。对3组病人术后感染率及输血量与感染率的关系进行比较。结果：普通悬浮红细胞输血组术后感染率为11．83％。悬浮去白细胞红细胞输血组术后的感染率为5．66％，未输血组术后感染率为5．41％，后二组与普通悬浮红细胞输血组比较差异有统计学意义（P〈0．05），输悬浮去白细胞红细胞组与未输血组比较差异无统计学意义（P〉0．05）。结论：输血与肝、脾外伤病人术后感染的发生率有关，并抑制伤口的愈合，以输普通悬浮红细胞组明显。提示对外伤病人应严格掌握输血指征，必须输血者应采用成分输血。

Objective：To investigate effect of blood transfusion on postoperative infection of liver and spleen after closed trauma , and guide blood transfusion reasonably. Methods：220 patients underwent liver and spleen closed trauma operation ofter closed trauma in our hospital during 2004 -2006.93 patients received transfusion of ordinary suspension red cells,53 patients received transfusion of suspension red cells with white blood cells remored ,74 patients without transfusion. To compare the postoperative infection among the three groups and the infection rate with transfusion capacity. Results ：The post- operative infection rate of the patients transfused with ordinary suspension red cell was 11.83%, suspension red cell with white blood cell group was 5.66% ,and in the without transfusion group was 5.41%. There are significance of the difference between the ordinary suspension red cell group and the other two groups （P 〈 0. 05） ; there are no difference between suspension red cell without white blood cell group and without transfusion group（ P 〉 0.05）. Conclusion： Blood transfusion could increase the post - operative infection in the patients of liver and spleen closed trauma, especially transfused with ordinary suspension red ceils. This study hints that the transfusion criterion should be controlled strictly, and those who need blood transfusion should be treated with component blood transfusion.