摘要
瘦素是脂肪组织表达的一种调节能量的激素。随着对瘦素的进一步研究,人们对其作用已不再限于肥胖和消瘦的范畴。瘦素与肿瘤血管的生成和肿瘤生长、转移密切相关;瘦素参与了肿瘤的病理生理过程。
出处
《中国现代医生》
2007年第12S期148-149,共2页
China Modern Doctor
参考文献10
-
1Stattin P,Soderberg S,Hallmans G,et al.Leptin is associated with in-creased prostate cancer risk:a nested case-referent study[].Journal of Clinical Endocrinology and Metabolism.2006
-
2Shida D,Kitayama J,Mori K,et al.Trantsactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase2and extracellular signal-regulated kinase1/2in human gastric cancer cells[].Cancer Research.2005
-
3Hardwick JC,van Santen M,van den Brink GR,et al.DNA array analysis of the effects of aspirin on colon cancer cells:involvement of Racl[].Carcinogenesis.2004
-
4Elinav E,Abd-Elnsabi A,Pappo O,et al.Suppression of hepatocellular carcinoma growth in mice via lepfin,is associated with inhibition of tu-mor cell growth and natural killer cell activation[].Journal of Hepatology.2006
-
5Barber MD,MeMillan DC,Wallace AM,et al.The response of leptin.interleukin-6and fat oxidation to feeding in weight-losing patients with pancreatic cancer[].British Journal of Cancer.2004
-
6Bruserud O,Huang TS,Glenjen N,et al.Leptin in human acute myel-ogenous leukemia:studies of in vivo levels and in vitro effects on native functional leukemia blastr[].Haematologica.2002
-
7Chang S,Hursting SD,Contois JH,et al.Leptin and prostate cancer[].Prostate.2001
-
8Ozet A,Arpaci F,Yilmaz MI, et al.Effects of tamoxifen on the serum leptin level in pa- tients with breast cancer[].Jpn J Clin Oncol.2001
-
9Mix H,Widjaja A,Jandla O,et al.Expression of leptin and leptin re-ceptor isoforms inthe human stomach[].Gut.2000
-
10Pai R,Lin C,Tran T, et al.Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation[].Biochemical and Biophysical Research Communications.2005
同被引文献20
-
1Janice Hopkins Tanne,顾佳.高动物脂肪饮食增加患乳腺癌风险,而止痛药可降低风险[J].英国医学杂志中文版,2004,7(3):143-144. 被引量:2
-
2李青,马钰.脂肪组织功能新发现[J].中华病理学杂志,2006,35(6):363-364. 被引量:5
-
3Maria Eugenia Frigolet Va'zquez - Vela. White Adipose Tissue as Endocrine Organ and Its Role in Obesity [ J ]. Archives of Medical Research ,2008,39:715 - 728.
-
4Zuk PA, Zhu M, Hedrick MH, et al. Multipotent cells from humanadipose tissue implications for cell - based therapies [ J ]. Tissue Eng,2001,7(2) :221 -226.
-
5Mauney JR, Volloch V, Kaplan DL. Matrix - ediated retention of adipogenic differentiation potential by human adult bone marrow derived mesenchymal stem cells during exvivo expansion [ J ]. Biomaterials,2005,26 (31) :6167 -6175.
-
6Patricia A Zuk, Min Zhu, Peter Ashjian, et al. Human adipose tissue is a source of muhipotent stem cells [J]. Moleeul Biolog Cell, 2002,12( 13 ) :4279 -4295.
-
7Rodriguez AM, Elabd C, Deheil F, et al. Adipocyte differentiation of multipotent cells established from human adipose tissue [ J ]. Biothem Biophys Res Commun,2004,315 (2) :255 -263.
-
8Jarde T, Caldefie - Chezet F, Goncalves - Mendes N, et al. Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies[J]. Endocrine - related Cancer,2009,16 (4) : 1197 - 1210.
-
9Maceio A, Madeddu C, Mantovani G. Adipose tissue as target organ in the treatment of hormone - dependent breast cancer: new therapeutic perspectives [ J ]. Obesity Reviews, 2009,10 ( 6 ) : 660 - 670.
-
10Vona - Davis L, Rose DP. Angiogenesis, adipokines and breast cancer[J]. Cytokine & Growth Factor Reviews,2009,20 ( 3 ): 193 -201.
二级引证文献3
-
1张沙沙,易景娜.女大学生对乳腺癌年轻化的认知及对策[J].河南医学高等专科学校学报,2016,28(5):460-461. 被引量:4
-
2许军婷,李海峰,宋金莲,华亚男,侯琳.慢病毒介导的RNA干扰沉默RRS1基因对乳腺癌细胞MCF-7生物学行为的影响[J].精准医学杂志,2018,33(1):75-80. 被引量:1
-
3吴敏,孙敬蒙,张炜煜.动物类脂肪酸脱氢酶研究进展[J].吉林中医药,2020,40(5):689-692. 被引量:2
-
1袁仙仙,陶红,来永强,李进华,戴江,张福庄,龚凤英,辛毅,黄真茹,周迎生,赵怡.冠心病患者旁脂肪组织表达Chemerin对单核细胞黏附和迁移的影响[J].中国动脉硬化杂志,2013,21(9).
-
2孙斐,俞瑾.神经肽Y在能量平衡和生殖调节中的作用[J].现代妇产科进展,1999,8(1):68-71. 被引量:11
-
3陈锐,朱尤庆.脑肠肽Ghrelin的研究进展[J].武汉大学学报(医学版),2010,31(3):417-420. 被引量:10
-
4耿彬.脂肪内源性硫化氢-功能、调节与疾病[J].生理科学进展,2017,48(1):37-41. 被引量:3
-
5毕小朵,张称心.瘦素、血小板活化因子在新生儿生长发育中的作用[J].临床荟萃,2012,27(3):228-230. 被引量:1
-
6许欢妮,尹卫东.AMPK及脂肪细胞因子调节胰岛素抵抗的研究进展[J].现代生物医学进展,2009,9(22):4381-4383. 被引量:4
-
7张秀锦,叶平,王兆君.衰老后PPARγ目标基因表达的改变与胰岛素抵抗的关系[J].中国老年学杂志,2004,24(4):327-328. 被引量:3
-
8张颖,刘宁,任青爱,张海峰,谢晓华.硫氢化钠防治截肢术后大鼠肾脏损伤的机制[J].南方医科大学学报,2013,33(8):1146-1150. 被引量:5
-
9王斌,章卫平.瘦素调节下丘脑神经肽Agouti相关蛋白表达的研究进展[J].第二军医大学学报,2009,30(5):569-572. 被引量:10
-
10陈艳芳,刘培庆,汪煜华.转录辅抑制因子RIP140在代谢组织中的作用及机制[J].中国药理学通报,2010,26(6):701-704. 被引量:2