有机锡氧簇合物选择性催化醛的硅氢化反应研究

Study on Aldehyde Hydrosilylation Selectively Catalyzed by Organotin Oxo Cluster

有机锡氧簇合物在有机合成反应中体现出良好的催化活性.以Bu2SnO与TfOH(OTf=CF3SO3)直接反应合成了有机锡氧簇合物[Bu2Sn(OH)OTf]2,考察了[Bu2Sn(OH)OTf]2催化醛的硅氢化反应.结果表明不仅催化活性高,而且具有很高的选择性.它仅对反应物的醛基起作用,对分子内和反应体系中其它活泼基团如酮、酯、烯、炔等不起作用.

The organotin oxo clusters show excellent catalytic activity to many organic synthetic reactions. In this paper, a kind of organotin oxo cluster [Bu2Sn（OH）OTf]2 （OTf= CF3SO3） was synthesized by Bu2SnO and TfOH simply, and the reductions of aldehydes catalyzed by [Bu2Sn（OH）OTf]2 were studied. The results showed that [Bu2Sn（OH）OTf]2 had excellent activity and selectivity. Only the aldehyde groups could be catalyzed, while the competitive groups such as ketone, ester, alkene, alkyne groups in one molecule or competitive compounds in one reaction system could not be catalyzed.