摘要
以双长链烷基磷酸酯为脂质体膜材，聚季铵化合物为包覆材料制备了网络化脂质体，通过偏光显微镜观察了脂质体形态，研究了脂质体的制备方法、包封率及释药性能．
Deorganylation tendency between tri(2 benzofuryl) borane、tri(2 furyl) borane and tri(2 thienyl) borane with some β diketones (Acetylacetone、Dibenzoylmethane、Ferrocenoylacetone) was compared,and losing organyl group ability of the resulted diorganylboroium β diketonates in their EI MS reactions was observed also.The results indicated that Symbiosis among the rather soft heteroaryl units bonding to Boron atom renders its B—C bond resistant to the breakage,accordingly,the cleavage of 2 benzofuryl、2 furyl group as symbiotic ligands from boron atom is more difficult than 2 thienyl group as unsymbiotic ligand.
出处
《武汉大学学报（自然科学版）》
CSCD
1997年第4期453-457,共5页
Journal of Wuhan University(Natural Science Edition)
基金
国家自然科学基金
关键词
磷酸酯
脂质体
药物控制释放
网络化
borane,boron chelates,β diketone,heterocyclic compounds,deorganylation,symbiosis,symbiotic ligand
