摘要在国外,围产期指产前三周至产后两周,其中,产前三周为围产前期,产后两周为围产后期。围产期奶牛的能量负平衡导致激素反应(Bauman and Currie,1980),引起脂肪组织的脂解作用增强,肝脏的糖酵解增强,直接和间接地损害了肝脏脱氨生成尿素的能力,从而降低了肝脏合成葡萄糖的能力。本文通过营养供给来减少肝脏中甘油三酯的积累,预防脂肪肝,实现围产期奶牛肝脏的代谢健康。
1Bauman,D.E.,and W.B.Currie.Partitioning of nutrients during pregnancy and lactation:A review of mechanisms involving homeostasis and homeorhesis[J].J.Dairy Sci.1980,63:1514-1529.
2Emery,R.S.,J.S.Liesman,and T.H.Herdt.Metabolism of longchain fatty acids by ruminant liver[J].J.Nutr.1992,122:832-837.180.
3Overton,T.R.,J.K.Drackley,G.N.Douglas,L.S.Emmert,and J.H.Clark.Hepatic gluconeogenesis and wholebody protein metabolism ofperiparturient dairy cows as affected by source of energy and intake ofthe prepartum diet[J].J.Dairy Sci.1998,81(Suppl.1):295.
4Overton,T.R.,J.K.Drackley,C.J.Ottemann-Abbamonte,A.D.Beaulieu,L.S.Emmert,and J.H.Clark.Substrate utilization for hepaticgluconeogenesis is altered by increased glucose demand in ruminants[J].J.Anim.Sci.1999,77:1940-1951.
5Drackley,J.K.Biology of dairy cows during the transition period:the final frontier[J].J.Dairy Sci.1999,82:2259-2273.
6Strang,B.D.,S.J.Bertics,R.R.Grummer,and L.E.Armentano.Effect of long-chain fatty acids on triglyceride accumulation,gluconeogenesis,and ureagenesis in bovine hepatocytes[J].J.Dairy Sci.1998,81:728-739.
7Zhu,L.H.,L.E.Armentano,D.R.Bremmer,R.R.Grummer,and S.J.Bertics.Plasma concentration of urea,ammonia,glutamine Around calving,and the relation of hepatic triglyceride,to plasma ammonia removal and blood acid-base balance[J].J.Dairy Sci.2000,83:734-740.
8Reynolds,C.K.,P.C.Aikman,D.J.Humphries,and D.E.Beever.Splanchnic metabolism in transition dairy cows[J].J.Dairy Sci.2000a,83(Suppl.1):257.
9Reynolds,C.K.,B.Durst,D.J.Humphries,B.Lupoli,A.K.Jones,R.H.Phipps,and D.E.Beever.Visceral tissue mass in transitiondairy cows.J.Dairy Sci.2000b,83(Suppl.1):257.
10Cadorniga-Valino,C.,R.R.Grummer,L.E.Armentano,S.S.Donkin,and S.J.Bertics.Effects of fatty acids and hormones on fatty acid metabolism and gluconeogenesis in bovine hepatocytes[J].J.Dairy Sci.1997,80:646-656.
