摘要
目的观察壳聚糖对肝癌细胞SMMC7721的生长抑制作用。方法采用MTr法研究了不同浓度水溶性壳聚糖对肝癌细胞株SMMC7721的生长抑制作用。结果水溶性壳聚糖可抑制肝癌细胞的生长，在一定范围内（50—400m∥L）呈剂量依赖关系。结论水溶性壳聚糖对肝癌细胞的生长有抑制，并且呈剂量依赖关系。
Objective To study the effect of chitosans for Antiproliferation in hepatocellular carcinoma （HCC） cell lines（SMCC7721）. Methods HCC line SMMC7721 was treated with different concentration of Water-solubility chitosan and antiproliferation effects was measured by MT＇F methed at 72hagesults Water-solubility chitosan had the effect of inhibition on the growth of hepatocarcinoma cells SMMC7721,which were enhanced along with increase of concentration in a range （50- 400mglL）.Conclusion Chitosmm could inhibit the growth of HCC cell line in vitro, and the inhibit was dose-depending .
出处
《江西医药》
CAS
2007年第11期987-988,共2页
Jiangxi Medical Journal
基金
江西省自然科学基金资助项目(NO.0440105)
江西省科技攻关项目(NO.332)
关键词
壳聚糖
肝癌细胞
生长抑制
chitosans
hepatocellular carcinoma
antiproliferation
