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吉西他滨联合顺铂治疗晚期食管癌近期临床观察

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摘要 目的观察吉西他滨+顺铂联合化疗治疗晚期食管癌的疗效和不良反应。方法可评价疗效的晚期食管癌病人31例.吉西他滨,d1,8,1000mg/m^2静脉滴注:顺铂,d1~3,80mg/m^2;21d为一个周期。观察疗效和不良反应。结果可评价疗效者31例,其中CR1例(3.2%),PR16例(51.6%),总有效率为54.85%。毒副反应主要是骨髓抑制和胃肠道反应,治疗有效的病人进食困难和胸痛均缓解。结论吉西他滨+顺铂治疗晚期食管癌可获得较高疗效,临床获益率高,毒副反应能耐受.为晚期食管癌的治疗提供了一种新的选择。
出处 《江西医药》 CAS 2007年第11期1018-1020,共3页 Jiangxi Medical Journal
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