期刊文献+

线粒体融合蛋白Mfn1/2的结构和功能 被引量:9

下载PDF
导出
摘要 线粒体融合素基因(mitofusin gene,Mfn)在哺乳动物中编码两种蛋白质分子,Mfn1和Mfn2,它们在线粒体融合、分裂与细胞凋亡中起重要作用,调控着线粒体形态的动态变化。另外,Mfn1/2还参与线粒体的能量代谢并与相关疾病的发生有着密切关系。
出处 《生命的化学》 CAS CSCD 北大核心 2007年第6期511-513,共3页 Chemistry of Life
基金 河北省自然科学基金资助项目(No.2007000894) 国家自然科学基金资助项目(No.30770247)
  • 相关文献

参考文献22

  • 1Karbowski M et al. Cell Death Differ, 2003, 10(8): 870-880
  • 2Chen H et al. J Cell Biol, 2003, 160(2): 189-200
  • 3Rojo M et al. J Cell Sci, 2002, 115(8): 1663-1674
  • 4Chen H et al. J Biol Chem, 2005, 280(28): 26185-26192
  • 5Koshiba T et al. Science, 2004, 305(5685): 858-862
  • 6Ishihara N et al. J Cell Sci, 2004, 117(26): 6535-6546
  • 7Santel A et al. J Cell Biol, 2003, 116(13): 2763-2774
  • 8Eura Y et al. J Biochem, 2003, 134(3): 333-344
  • 9Lee YJ et al. Mol Biol Cell, 2004, 15(11): 5001-5011.
  • 10Karbowski M et al. J Cell Biol, 2002, 159(6): 931-938

二级参考文献26

  • 1DEPREE W,TAEGTMEYER H.Metabolic aspects of programmed cell survival and cell death in the heart[J].Cardiovasc Res,2000,45(8):530-538.
  • 2VAN HEERDE W L,ROBERT O,DUMONT E,et al.Markers of apoptosis in cardiovascular tissue:focus on Annexin V[J].Cardiovasc Res,2000,45(9):542-549.
  • 3CHEN K H,GUO X,MA D,et al.Deregulation of HSG triggers vascular proliferative disorders[J].Nat Cell Biol,2004,6(9):872-883.
  • 4MACFDEN R J.Role of the circulating and tissue based rennin angiotensin system in the development of heart failure implications for therapy[J].Cardiology,1993,83(6):38-48.
  • 5HASENFUSS G.Alterations of calcium regulatory proteins in heart failure[J].Cardiovasc Res,1998,37(5):279-289.
  • 6CHEN K H,TANG J,MA D L,et al.Cloning and expression of a novel cDNA related to hypertension[J].Chin Med J,1998,111(8):384-386.
  • 7MATTSON M P,KROEMER G.Mitochondria in cell death:novel targets for neuroprotection and cardioprotection[J].Trends Mol Med,2003,9 (5):196-205.
  • 8DATTA S R,BRUNET A,GREENBERG M E.Cellular survival:play in three Akts[J].Genes Dev,1999,13(8):2905-2927.
  • 9DATTA S R.Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery[J].Cell,1997,91(6):231-241.
  • 10CANTLEY L C.The phosphoinositide 3-Kinase pathway[J].Science,2002,296(5):1655-1657.

共引文献19

同被引文献99

引证文献9

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部