成人体重指数和总体脂肪与血脂异常的相关性

Relationship between Body Mass Index,Total Body Fat,and Dyslipidemia

目的观察成人体重指数(BMI)、总体脂肪率及分布与血脂异常的相关性。方法对2006年1月至2007年4月在北京协和医院接受年度查体的302例健康成人进行横断面调查,采用多频生物电阻抗测定体重(BW)、总体脂肪(TBF)、腹部脂肪(AF)、内脏脂肪(VF)、内脏脂肪面积(VFA)和腰臀围比值(WHR),同时测定血清甘油三酯(TG)、总胆固醇(CHO)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C),分析BMI、TBF及分布与血脂异常的相关性。结果男性BMI肥胖和超重的发生率、WHR异常和血脂异常的发生率均显著高于女性(P<0.05),但女性表现为TBF%显著增高(P<0.05)。超重和肥胖组的TBF、WHR、AF、VF、VFA、CHO、TG和LDL-C均显著高于体重正常组(P<0.05)。血脂正常组,女性BMI和TBF与CHO、TG和LDL-C呈正相关(P<0.05),与HDL-C呈负相关(P<0.05)。血脂异常组,男性和女性均表现为BMI和TBF与TG呈正相关(P<0.05),男性BMI和TBF与TG和HDL-C呈负相关(P<0.05)。结论肥胖/超重和体脂总量超标可增加成年男性和女性血脂异常的发生风险。

Objective To investigate the relationship between body mass index （BMI）, total body fat （TBF）, body fat distribution and dyslipidemia in adults. Methods A cross-sectional study was conducted in 302 healthy subjects who had yearly examination at PUMC Hospital from Jan. 2006 to Apr. 2007. Body weight （BW）, TBF, abdomen fat （AF） , visceral fat （VF） , visceral fat area （VFA） and waist-to-hip ratio （WHR） were measured by multi-frequency bioelectric impedance analysis. Serum triglyceride （TG）, total cholesterol （CHO）, HDL-C and LDL-C were measured at the same time. Results The incidence of obesity/overweight, abnormal WHR and dyslipidemia in male was more higher than that in female （ P 〈 0. 05 ） and the significant increase of TBF% in female was observed. TBF, WHR, AF, VF, VFA, CHO, TG, and LDL-C in obesity/overweight group were more higher than those in normal weight group （P 〈 0. 05 ）. In normal lipid females, BMI and TBF showed significant positive or negative correlation with CHO, TG, and LDL （P 〈 0. 05 ） or HDL （P 〈 0. 05 ） respectively. In dyslipidemia group, the positive correlation between BMI and TBF was observed in both of males and females （P 〈 0. 05 ）. And the negative correlation between BMI and TBF was observed in males （P 〈0. 05）. Conclusion Obesity/overweight and hyper-TBF increased the risk of dyslipidemia significantly both in male and female adults.