早期自发流产妇女血清抗子宫内膜抗体的研究

Study of endometrial antibodies in early spontaneous abortion women's serum

采用酶联免疫吸附试验 (EL ISA)对 10 5例早期自发流产妇女血清中抗子宫内膜抗体 (EMAb)进行检测 ,并与正常生育组对照研究。结果表明 ,早期自发流产妇女血清中 EMAb的阳性率显著高于正常生育组 (P<0 .0 1)。流产 1次与流产 2次相比 ,血清中 EMAb阳性率无明显差异 (P>0 .0 5) ;流产 3次或 3次以上与流产 1～ 2次相比 ,血清 EMAb阳性率明显降低 (P<0 .0 5)。提示 EMAb是早期自发流产的一个重要原因 ,且对流产 1～ 2次者影响较为明显。

Enzyme linked immunosorbent assay (ELISA) was used to detect the endometrial antibodies(EMAb) in the women's serum with early spontaneous abortion.The results showed that the positive rate of EMAb in early spontaneous abortion women is much higher than that in normal pregnant women ( P <0.01).The positive rate of EMAb in the women with 3 times or more than 3 times abortion is lower than that in the women with abortion once and twice( P <0.05).These results indicate that EMAb is an important reason for early spontaneous abortion.