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特比萘芬致味觉丧失 被引量:5

Ageusia produced by terbinafine
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摘要 1名55岁女性,因患甲癣口服特比萘芬250mg,1次/d。约1个月后,患者感觉对咸、苦等味道不敏感。继续服药1月余,其味觉完全丧失,遂停药。随访20d,患者味觉未恢复。 A 55-year-old woman received oral terbinafine 250 mg once daily for onychomycosis, About one month later, she developed decreased sensitivity to salty and bitter taste, More than one month after continuation of terbinafine, she had a total loss of the ability to taste. Terbinafine was discontinued. Her taste sense did not recover during 20 days of follow-up.
作者 张弨 翟所迪
出处 《药物不良反应杂志》 2007年第6期426-426,共1页 Adverse Drug Reactions Journal
关键词 特比萘芬 味觉丧失 terbinafine ageusia
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参考文献6

  • 1Hall M, Krupp P, Monka C, et al. Safety of oral terbinafine: results of a postmarketing surveillance study in 25 884 patients[J]. Arch Dermotol, 1997, 33(10) : 1213- 1219.
  • 2胡燕.口服特比萘芬引起不良反应3例[J].中国麻风皮肤病杂志,2005,21(7):553-554. 被引量:5
  • 3Bong JL, Lucke TW, Evans CD. Persistent impairment of taste resulting from terbinafine[ J]. B J Dermatol, 1998, 139(4) :747-748.
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二级参考文献6

  • 1Hall M, Monka C, Krupp P, et al. Safety of oral terbinafine: results of a postmarketing surveillance study in 25,884 patients. Arch Dermatol 1997; 33:1213 - 1219.
  • 2O'Sullivan DP, Needham CA, Bangs A, et al. Postmarketing surveillance of oral terbinafine in the UK: report of a large cohort study. Br J Clin Pharmacol 1996;42:559 - 565.
  • 3Taberner R, Puig L, Gilaberte M, et al. Acute generalized exanthematous pustulosis induced by terbinafine. Eur J Dermatol 2003;13: 313 - 314.
  • 4Carstens J, Wendelboe P, Sogaard H, et al. Toxic epidermal necrolysis and erythema multiforme following therapy with terbinafine. Acta Derm Venereol 1994;74:391 - 392.
  • 5Gupta AK, Lynde CW, Lauzon GJ, et al. Cutaneous adverse effects associated with terbinafine therapy: 10 case reports and a review of the literature. Br J Dermatol 1998; 138:529- 532.
  • 6Rzany B, Mockenhaupt M, Gehring W, et al. Stevens- Johnson syndrome after terbinafine therapy. J Am Acad Dermatol 1994; 30:509.

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