经皮腹腔神经丛阻滞治疗癌性疼痛

Neurolytic Celiac Plexus Block in Cancer Pain Management

目的:评价CT引导下经皮腹腔神经丛阻滞(NCBP)治疗癌性疼痛的安全性和疗效。方法:11例晚期肿瘤伴持续性疼痛患者,在CT引导下采用双侧后路膈脚前阻滞法阻滞腹腔神经丛。结果:11例NCBP技术成功率100%。术后1周完全缓解(CR)7例、部分缓解(PR)3例、轻度缓解(MR)1例,有效率90.9%。术后2个月CR:5例、PR:3例、MR:3例,有效率72.7%。3例发生体位性低血压,3例出现轻中度腹泻。结论:CT引导下经皮腹腔神经丛阻滞治疗癌性疼痛,是一种安全、有效的方法。

Objective：To evaluate the safety and efficacy of neurolytic celiac plexus block （NCBP） in controlling pain due to upper abdominal malignancies. Methods： 11 patients with advanced malignancies accepted NCBP. All procedures were performed via pre-crus of diaphragm approach under CT guidance. Results： The technical success was 100% in 11 cases. 1 week after the procedure, CR （complete relief）, PR （partial relief）, and MR （moderate relief） were achieved in 7, 3 and 1 patients respectively, producing the effective rate of 90.9%. 2 months after the procedure, CR, PR, and MR were achieved in 5, 3 and 3 patients respectively, producing the effective rate of 72.7%. Postural hypotension occurred in 3 patients, and diarrhea occurred in 3 patients. Conclusion：NCBP is a safe and effective treatment in controlling pain due to upper abdominal malignancies.